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Rabbit anti-Rat Connexin 31.1 Polyclonal Antibody | anti-GJB5 antibody

Connexin 31.1 (CX31.1.1, Gap Junction Beta 5 Protein, CXB-5)

Gene Names
GJB5; CX31.1
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by immunoaffinity chromatography.
Synonyms
Connexin 31.1; Polyclonal Antibody; Connexin 31.1 (CX31.1.1; Gap Junction Beta 5 Protein; CXB-5); Anti -Connexin 31.1 (CX31.1.1; anti-GJB5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat Connexin 31.1 Does not have significant homology with other known Connexins. Species sequence homology: mouse
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in 100mM Tris, pH 7.5, 0.2% BSA, 0.05% sodium azide, before the addition of 40% glycerol.
Applicable Applications for anti-GJB5 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1-10ug/ml using ECL.
ELISA: 1:100K using 50-100ng CX31.1 control peptide/well.
Optimal dilutions to be determined by the researcher
Immunogen
A 14 amino acid synthetic peptide C-terminal, cytoplasmic of rat Cx31.1 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Product Categories/Family for anti-GJB5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
31,088 Da
NCBI Official Full Name
connexin 31.1
NCBI Official Synonym Full Names
gap junction protein, beta 5, 31.1kDa
NCBI Official Symbol
GJB5
NCBI Official Synonym Symbols
CX31.1
NCBI Protein Information
gap junction beta-5 protein; connexin 31.1; connexin-31.1; OTTHUMP00000004186; gap junction protein, beta 5 (connexin 31.1)
UniProt Protein Name
Gap junction beta-5 protein
UniProt Gene Name
GJB5
UniProt Entry Name
CXB5_HUMAN

NCBI Description

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family.[supplied by OMIM]

Uniprot Description

GJB5: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Beta-type (group I) subfamily.

Protein type: Membrane protein, integral; Cell adhesion; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p35.1

Cellular Component: connexon complex; integral to membrane

Biological Process: epidermis development; cell communication

Research Articles on GJB5

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Product Notes

The GJB5 gjb5 (Catalog #AAA617966) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Connexin 31.1 (CX31.1.1, Gap Junction Beta 5 Protein, CXB-5) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Connexin 31.1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1-10ug/ml using ECL. ELISA: 1:100K using 50-100ng CX31.1 control peptide/well. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the GJB5 gjb5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Connexin 31.1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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