Goat anti-Human Complement C4 Polyclonal Antibody | anti-C4a antibody
Complement C4 antibody
Gene Names
C4a; C4; C4b; C4-1
Reactivity
Human
Applications
ELISA, Immunodiffusion, Western Blot
Synonyms
Complement C4; Polyclonal Antibody; Complement C4 antibody; Polyclonal Complement C4; Anti-Complement C4; Complement C -4; Complement C 4; C4; anti-C4a antibody
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Specificity
Human
Form/Format
Frozen liquid with 0.09 % NaN3.
Sequence Length
1737
Applicable Applications for anti-C4a antibody
ELISA (EIA), Immunodiffusion, Western Blot (WB)
Application Notes
ELISA: 1:256,000
Immunodiffusion: 1:8
WB: 1:128,000
Immunodiffusion: 1:8
WB: 1:128,000
Biological Significance
Complement component 4 is a protein involved in the complement system. It is cleaved into proteins 4a and 4b. C4a is an anaphylatoxin. C4b forms part of C3-convertase, in conjunction with 2a. C4b can bind CR1. C4d is the final proteolytic remnant of deposited C4b on endothelium, it remains covalently attached to endothelium for little more than a week and is easily detectable by antibody staining.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
Complement C4 antibody was raised in goat using highly purified human complement protein as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-C4a antibody
Goat polyclonal Complement C4 antibody
Product Categories/Family for anti-C4a antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
192,163 Da
NCBI Official Full Name
complement C4
NCBI Official Synonym Full Names
complement component 4A (Rodgers blood group)
NCBI Official Symbol
C4a
NCBI Official Synonym Symbols
C4; C4b; C4-1
NCBI Protein Information
complement C4
UniProt Protein Name
Complement C4
Protein Family
UniProt Gene Name
C4
UniProt Synonym Gene Names
C4a
UniProt Entry Name
CO4_RAT
NCBI Description
complement protein, part of the classical activation pathway; localizes to the class III region of the MHC [RGD, Feb 2006]
Uniprot Description
C4A: Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory processes. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes
Protein type: Secreted, signal peptide; Inhibitor; Secreted
Cellular Component: extracellular space; extracellular region
Molecular Function: complement component C1q binding; endopeptidase inhibitor activity
Biological Process: innate immune response; inflammatory response; complement activation, classical pathway; complement activation
Research Articles on C4a
Similar Products
Product Notes
The C4a c4 (Catalog #AAA536289) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Complement C4 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Complement C4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunodiffusion, Western Blot (WB). ELISA: 1:256,000 Immunodiffusion: 1:8 WB: 1:128,000. Researchers should empirically determine the suitability of the C4a c4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Complement C4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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