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Immunohistochemistry (IHC) (Anti-Complement C4b antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Goat anti-Human Complement C4 Polyclonal Antibody | anti-C4a antibody

Anti-Complement C4 Antibody

Gene Names
C4a; C4; C4b; C4-1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antiserum
Synonyms
Complement C4; Polyclonal Antibody; Anti-Complement C4 Antibody; Rat Monoclonal (IgG2a) to Mouse Complement C4; anti-C4a antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Monospecific to human complement component C4 (pooled normal human plasma and pooled 2X conc. human serum, IEP). Recognizes C4b, C4a and whole complement C4.
Purity/Purification
Antiserum
Form/Format
TBS, pH 7.5, 0.1% sodium azide.
Sequence Length
1737
Applicable Applications for anti-C4a antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin
Application Notes
IHC-P: 1:100
Immunogen
Human complement component C4.
Conjugation
Unconjugated
Preparation and Storage
Short term: 4 degree C
Long term: -20 degree C.
Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-Complement C4b antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-Complement C4b antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (WB)

(Anti-Complement C4b antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)

Immunohistochemistry (WB) (Anti-Complement C4b antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Related Product Information for anti-C4a antibody
protein involved in the complement system. It is cleaved into protein s4a and 4b; 4b can be further cleaved into 4c and 4d. C4a is ananaphylatoxin. C4b forms part of C3-convertase, in conjunction with 2a, and can bind CR1. C4d has been identified as a biomarker for systemiclupus erythematosus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
192,163 Da
NCBI Official Full Name
complement C4
NCBI Official Synonym Full Names
complement C4A
NCBI Official Symbol
C4a
NCBI Official Synonym Symbols
C4; C4b; C4-1
NCBI Protein Information
complement C4
UniProt Protein Name
Complement C4
Protein Family
UniProt Gene Name
C4
UniProt Synonym Gene Names
C4a

NCBI Description

complement protein, part of the classical activation pathway; localizes to the class III region of the MHC [RGD, Feb 2006]

Uniprot Description

Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes ().

Research Articles on C4a

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Product Notes

The C4a c4 (Catalog #AAA2400900) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Complement C4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Complement C4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin. IHC-P: 1:100. Researchers should empirically determine the suitability of the C4a c4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Complement C4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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