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Immunohistochemistry - Paraffin (IHC) (Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit CO-029 / TSPAN8 Polyclonal Antibody | anti-CO-029 / TSPAN8 antibody

Anti-CO-029 / TSPAN8 Antibody (aa110-160) IHC-plus

Gene Names
TSPAN8; CO-029; TM4SF3
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity purified
Synonyms
CO-029 / TSPAN8; Polyclonal Antibody; Anti-CO-029 / TSPAN8 Antibody (aa110-160) IHC-plus; Rabbit Polyclonal to Human CO-029 / TSPAN8; Human CO-029 / TSPAN8; TM4SF3; Tspan-8; Tetraspanin 8; Tetraspanin-8; anti-CO-029 / TSPAN8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
Human CO-029 / TSPAN8
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, pH 7.2, 0.05% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
237
Applicable Applications for anti-CO-029 / TSPAN8 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)
Immunogen
CO-029 / TSPAN8 antibody was raised against synthetic peptide around Ser129 of human CO-029 / TSPAN8
Immunogen Description
Synthetic peptide around Ser129 of human CO-029 / TSPAN8
Immunogen Type
Synthetic peptide
Antigen Modification
aa110-160
Target Species
Human
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Immunohistochemistry - Paraffin (IHC)

(Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry - Paraffin (IHC) (Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot (WB) analysis of TSPAN8 pAb at 1:500 dilution. Lane 1: A549 whole cell lysate. Lane 2: NIH-3T3 whole cell lysate. Lane 3: PC12 whole cell lysate.)

Western Blot (WB) (Western blot (WB) analysis of TSPAN8 pAb at 1:500 dilution. Lane 1: A549 whole cell lysate. Lane 2: NIH-3T3 whole cell lysate. Lane 3: PC12 whole cell lysate.)
Related Product Information for anti-CO-029 / TSPAN8 antibody
TSPAN8 Antibody, CO-029 Antibody, TM4SF3 Antibody, Tspan-8 Antibody, Tetraspanin 8 Antibody, Tetraspanin-8 Antibody Description: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,044 Da
NCBI Official Full Name
tetraspanin-8
NCBI Official Synonym Full Names
tetraspanin 8
NCBI Official Symbol
TSPAN8
NCBI Official Synonym Symbols
CO-029; TM4SF3
NCBI Protein Information
tetraspanin-8
UniProt Protein Name
Tetraspanin-8
UniProt Gene Name
TSPAN8
UniProt Synonym Gene Names
TM4SF3; Tspan-8
UniProt Entry Name
TSN8_HUMAN

NCBI Description

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

TSPAN8: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q14.1-q21.1

Cellular Component: integral to plasma membrane

Molecular Function: integrin binding

Biological Process: cell surface receptor linked signal transduction; negative regulation of blood coagulation

Research Articles on CO-029 / TSPAN8

Similar Products

Product Notes

The CO-029 / TSPAN8 tspan8 (Catalog #AAA249519) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CO-029 / TSPAN8 Antibody (aa110-160) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CO-029 / TSPAN8 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P (10 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the CO-029 / TSPAN8 tspan8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CO-029 / TSPAN8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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