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Western Blot (WB) (Western blotAll lanes: CNTN4 antibody IgG at 1.79ug/ml+ HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 114,32,77 kDaObserved band size: 113 kDa)

Rabbit anti-Human CNTN4 Polyclonal Antibody | anti-CNTN4 antibody

CNTN4 Antibody

Gene Names
CNTN4; AXCAM; BIG-2
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
CNTN4; Polyclonal Antibody; CNTN4 Antibody; Contactin-4; Brain-derived immunoglobulin superfamily protein 2; BIG-2; anti-CNTN4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
1026
Applicable Applications for anti-CNTN4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Contactin-4 protein (C-250AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68161 / sc-68162 / sc-68856
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: CNTN4 antibody IgG at 1.79ug/ml+ HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 114,32,77 kDaObserved band size: 113 kDa)

Western Blot (WB) (Western blotAll lanes: CNTN4 antibody IgG at 1.79ug/ml+ HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 114,32,77 kDaObserved band size: 113 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue MBS7045279 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue MBS7045279 at dilution 1:100)
Related Product Information for anti-CNTN4 antibody
Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,655 Da
NCBI Official Full Name
contactin-4 isoform a
NCBI Official Synonym Full Names
contactin 4
NCBI Official Symbol
CNTN4
NCBI Official Synonym Symbols
AXCAM; BIG-2
NCBI Protein Information
contactin-4
UniProt Protein Name
Contactin-4
Protein Family
UniProt Gene Name
CNTN4
UniProt Synonym Gene Names
BIG-2
UniProt Entry Name
CNTN4_HUMAN

NCBI Description

This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

Uniprot Description

CNTN4: Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis. A chromosomal aberration involving CNTN4 has been found in a boy with characteristic physical features of 3p deletion syndrome (3PDS). Translocation t(3;10)(p26;q26). 3PDS is a rare contiguous gene disorder involving the loss of the telomeric portion of the short arm of chromosome 3 and characterized by developmental delay, growth retardation, and dysmorphic features. Belongs to the immunoglobulin superfamily. Contactin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 3p26.3

Biological Process: axon guidance; axonal fasciculation; axonogenesis; brain development; negative regulation of neuron differentiation; nervous system development; neurite development; neuron adhesion; regulation of synaptic plasticity

Research Articles on CNTN4

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Product Notes

The CNTN4 cntn4 (Catalog #AAA7045279) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNTN4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CNTN4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CNTN4 cntn4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNTN4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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