Western Blot (WB)
(Fig.1. Western Blot analysis of various cells using CNT2 Polyclonal Antibody.)
Rabbit CNT2 Polyclonal Antibody | anti-CNT2 antibody
CNT2 Polyclonal Antibody
Gene Names
SLC28A2; CNT2; HCNT2; SPNT1; HsT17153
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CNT2; Polyclonal Antibody; CNT2 Polyclonal Antibody; Rabbit Anti-CNT2 Polyclonal Antibody; SLC28A2; Sodium/nucleoside cotransporter 2; Concentrative nucleoside transporter 2; CNT 2; hCNT2; Na(+)/nucleoside cotransporter 2; Sodium-coupled nucleoside transporter 2; Sodium/purine nucleoside co-transporter; SPNT; Solute carrier; anti-CNT2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CNT2 Polyclonal Antibody detects endogenous levels of CNT2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; PBS Containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
658
Applicable Applications for anti-CNT2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:100-1:300
ELISA: 1:10000
IHC-P: 1:100-1:300
ELISA: 1:10000
Immunogen
Synthesized peptide derived from the internal region of human CNT2 at AA range: 340-420
Preparation and Storage
Stable for one year at -20 degree C from date of shipment.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Western Blot (WB)
(Fig.1. Western Blot analysis of various cells using CNT2 Polyclonal Antibody.)
Western Blot (WB)
(Fig.1. Western Blot analysis of various cells using CNT2 Polyclonal Antibody.)
Western Blot (WB)
(Fig.2. Western Blot analysis of 3T3 cells using CNT2 Polyclonal Antibody.)
Western Blot (WB)
(Fig.2. Western Blot analysis of 3T3 cells using CNT2 Polyclonal Antibody.)
Related Product Information for anti-CNT2 antibody
The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
sodium/nucleoside cotransporter 2
NCBI Official Synonym Full Names
solute carrier family 28 member 2
NCBI Official Symbol
SLC28A2
NCBI Official Synonym Symbols
CNT2; HCNT2; SPNT1; HsT17153
NCBI Protein Information
sodium/nucleoside cotransporter 2
UniProt Protein Name
Sodium/nucleoside cotransporter 2
UniProt Gene Name
SLC28A2
UniProt Synonym Gene Names
CNT2; CNT 2; hCNT2; SPNT
UniProt Entry Name
S28A2_HUMAN
Uniprot Description
SLC28A2: Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues. Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
Protein type: Transporter, SLC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 15q15
Cellular Component: membrane; integral to plasma membrane; plasma membrane
Molecular Function: purine nucleoside transmembrane transporter activity; nucleoside:sodium symporter activity; nucleoside binding
Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; purine nucleoside transport; transmembrane transport
Research Articles on CNT2
Similar Products
Product Notes
The CNT2 slc28a2 (Catalog #AAA9701738) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNT2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CNT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). WB: 1:500-1:2000 IHC-P: 1:100-1:300 ELISA: 1:10000. Researchers should empirically determine the suitability of the CNT2 slc28a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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