Rabbit anti-Human CNPY3 Polyclonal Antibody | anti-CNPY3 antibody

CNPY3, NT (CNPY3, CTG4A, ERDA5, PRAT4A, TNRC5, Protein canopy homolog 3, CTG repeat protein 4a, Expanded repeat-domain protein CAG/CTG 5, Protein associated with TLR4, Trinucleotide repeat-containing gene 5 protein) (MaxLight 550)

Cat. Num. AAA6287335

• Gene Names: CNPY3; CAG4A; ERDA5; TNRC5; PRAT4A
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CNPY3; Polyclonal Antibody; NT (CNPY3; CTG4A; ERDA5; PRAT4A; TNRC5; Protein canopy homolog 3; CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; Trinucleotide repeat-containing gene 5 protein) (MaxLight 550); Trinucleotide repeat-containing gene 5 protein; anti-CNPY3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.

• Applicable Applications for anti-CNPY3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CNPY3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-92 amino acids from the N-terminal region of human CNPY3.
• Conjugate: MaxLight550
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-CNPY3 antibody

PRAT4A is associated with the immature form of TLR4 (MIM 603030) and regulates its cell surface expression (Wakabayashi et al., 2006 [PubMed 16849487]).

Product Categories/Family for anti-CNPY3 antibody

Antibodies; Toll Like Receptors (TLR)

References

Wakabayashi, Y., et al. J. Immunol. 177(3):1772-1779(2006). Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003). Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003). Zhang, H., et al. Nat. Biotechnol. 21(6):660-666(2003). Margolis, R.L., et al. Hum. Genet. 100(1):114-122(1997).

NCBI and Uniprot Product Information

• NCBI GI #: 33942072
• NCBI GeneID: 10695
• NCBI Accession #: NP_006577.2
• NCBI GenBank Nucleotide #: NM_006586.3
• UniProt Accession #: Q9BT09; O15412; Q0P6I2; Q8NF54; Q8WTU8; Q9P0F2
• Molecular Weight: 5,773 Da
• NCBI Official Full Name: protein canopy homolog 3
• NCBI Official Synonym Full Names: canopy FGF signaling regulator 3
• NCBI Official Symbol: CNPY3
• NCBI Official Synonym Symbols: CAG4A; ERDA5; TNRC5; PRAT4A
• NCBI Protein Information: protein canopy homolog 3; CAG repeat containing; CTG repeat protein 4a; canopy 3 homolog; expanded repeat domain, CAG/CTG 5; expanded repeat-domain protein CAG/CTG 5; protein associated with TLR4; protein associated with Toll-like receptor 4A; trinucleoti
• UniProt Protein Name: Protein canopy homolog 3
• Protein Family: Protein canopy
• UniProt Gene Name: CNPY3
• UniProt Synonym Gene Names: CTG4A; ERDA5; PRAT4A; TNRC5
• UniProt Entry Name: CNPY3_HUMAN

NCBI Description

PRAT4A is associated with the immature form of TLR4 (MIM 603030) and regulates its cell surface expression (Wakabayashi et al., 2006 [PubMed 16849487]).[supplied by OMIM, Mar 2008]

Uniprot Description

TNRC5: Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptative immune responses. Belongs to the canopy family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: endoplasmic reticulum lumen

Molecular Function: receptor binding

Biological Process: toll-like receptor signaling pathway; innate immune response