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Western Blot (WB) (Western blot analysis of CNPase expression in HeLa (A), mouse brain (B), rat brain (C) whole cell lysates.)

Rabbit CNPase Polyclonal Antibody | anti-CNP antibody

Anti-CNPase Antibody

Gene Names
CNP; CNP1
Reactivity
Human, Rat, Monkey, Sheep
Applications
Western Blot, Immunoprecipitation
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
CNPase; Polyclonal Antibody; Anti-CNPase Antibody; 2'; 3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; anti-CNP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat, Monkey, Sheep
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CNPase protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
421
Applicable Applications for anti-CNP antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
WB (1/500 - 1/1000), IP (1/10 - 1/100)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CNPase. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of CNPase expression in HeLa (A), mouse brain (B), rat brain (C) whole cell lysates.)

Western Blot (WB) (Western blot analysis of CNPase expression in HeLa (A), mouse brain (B), rat brain (C) whole cell lysates.)

Immunohistochemistry (IHC)

()

Immunohistochemistry (IHC) ()
Related Product Information for anti-CNP antibody
Rabbit polyclonal antibody to CNPase

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,099 Da
NCBI Official Full Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
NCBI Official Synonym Full Names
2',3'-cyclic nucleotide 3' phosphodiesterase
NCBI Official Symbol
CNP
NCBI Official Synonym Symbols
CNP1
NCBI Protein Information
2',3'-cyclic-nucleotide 3'-phosphodiesterase; CNPase; 2', 3' cyclic nucleotide 3' phosphohydrolase
UniProt Protein Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
UniProt Gene Name
CNP
UniProt Synonym Gene Names
CNP; CNPase
UniProt Entry Name
CN37_HUMAN

Uniprot Description

CNP: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Exists as monomers and homodimers. Belongs to the cyclic nucleotide phosphodiesterase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phosphodiesterase; Cell development/differentiation; EC 3.1.4.37

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: microtubule; extracellular space; microvillus; pseudopodium; nucleoplasm; mitochondrial outer membrane; membrane; perinuclear region of cytoplasm; mitochondrial inner membrane; cytoplasm; plasma membrane; melanosome; nucleus

Molecular Function: cyclic nucleotide binding; RNA binding; 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity

Biological Process: synaptic transmission; substantia nigra development; axonogenesis; adult locomotory behavior; response to toxin; forebrain development; oligodendrocyte differentiation; response to lipopolysaccharide; microtubule cytoskeleton organization and biogenesis; regulation of mitochondrial membrane permeability; cyclic nucleotide catabolic process; aging

Research Articles on CNP

Similar Products

Product Notes

The CNP cnp (Catalog #AAA821831) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CNPase Antibody reacts with Human, Rat, Monkey, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's CNPase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). WB (1/500 - 1/1000), IP (1/10 - 1/100). Researchers should empirically determine the suitability of the CNP cnp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNPase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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