Western Blot (WB)
(Western blotAll lanes: CNIH2 antibody at 2ug/mlLane 1: U251 whole cell lysateLane 2: Mouse liver tissueLane 3: Mouse kidney tissueSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 19 kDaObserved band size: 19 kDa)
Rabbit anti-Human, mouse CNIH2 Polyclonal Antibody | anti-CNIH2 antibody
CNIH2 Antibody
Western Blot (WB)
(Western blotAll lanes: CNIH2 antibody at 2ug/mlLane 1: U251 whole cell lysateLane 2: Mouse liver tissueLane 3: Mouse kidney tissueSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 19 kDaObserved band size: 19 kDa)
Western Blot (WB)
(Western blotAll lanes: CNIH2 antibody at 2ug/mlLane 1: U251 whole cell lysateLane 2: Mouse liver tissueLane 3: Mouse kidney tissueSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 19 kDaObserved band size: 19 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7002017 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7002017 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunofluorescent analysis of A549 cells using MBS7002017 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunohistochemistry (IHC)
(Immunofluorescent analysis of A549 cells using MBS7002017 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an auxiliary subunit of the ionotropic glutamate receptor of the AMPA subtype. AMPA receptors mediate fast synaptic neurotransmission in the central nervous system. This protein has been reported to interact with the Type I AMPA receptor regulatory protein isoform gamma-8 to control assembly of hippocampal AMPA receptor complexes, thereby modulating receptor gating and pharmacology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Uniprot Description
CNIH2: Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. Belongs to the cornichon family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: cell junction; dendrite; dendritic shaft; dendritic spine; endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; Golgi membrane; postsynaptic density; postsynaptic membrane
Molecular Function: protein binding
Biological Process: cellular protein metabolic process; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; regulation of membrane potential; synaptic transmission, glutamatergic
Research Articles on CNIH2
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Product Notes
The CNIH2 cnih2 (Catalog #AAA7002017) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNIH2 Antibody reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CNIH2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the CNIH2 cnih2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNIH2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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