Western Blot (WB)
(Western Blot analysis of 3T3 cells using CNG-1beta Polyclonal Antibody)
Rabbit CNGB1 Polyclonal Antibody | anti-CNGB1 antibody
CNGB1 Antibody
ELISA: 1:10000
Western Blot (WB)
(Western Blot analysis of 3T3 cells using CNG-1beta Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of 3T3 cells using CNG-1beta Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of NIH-3T3 cells using CNG-1beta Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of NIH-3T3 cells using CNG-1beta Polyclonal Antibody)
NCBI and Uniprot Product Information
NCBI Description
In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Uniprot Description
CNGB1: an integral membrane protein that forms a heterooligomeric complex with CNGA1. A modulatory subunit of cyclic nucleotide-gated cation channels.
Protein type: Membrane protein, integral; Channel, cation; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16q13
Cellular Component: Golgi membrane; integral to plasma membrane; plasma membrane; intracellular cyclic nucleotide activated cation channel complex; terminal button
Molecular Function: protein binding; voltage-gated potassium channel activity; intracellular cAMP activated cation channel activity; intracellular cGMP activated cation channel activity; cGMP binding; cAMP binding; ligand-gated ion channel activity
Biological Process: phototransduction, visible light; cytosolic calcium ion homeostasis; organelle organization and biogenesis; sensory perception of smell; photoreceptor cell maintenance; rhodopsin mediated signaling; retinal homeostasis; regulation of membrane potential; regulation of rhodopsin mediated signaling; visual perception; transport; protein localization in organelle; detection of light stimulus involved in visual perception; protein heterotetramerization; cation transport
Disease: Retinitis Pigmentosa 45
Research Articles on CNGB1
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Product Notes
The CNGB1 cngb1 (Catalog #AAA7121893) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNGB1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CNGB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:10000. Researchers should empirically determine the suitability of the CNGB1 cngb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNGB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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