Rabbit CLOSTRIDIUM DIFFICILE TOXIN A Polyclonal Antibody | anti-toxA antibody
RABBIT ANTI CLOSTRIDIUM DIFFICILE TOXIN A
Applications
ELISA
Synonyms
CLOSTRIDIUM DIFFICILE TOXIN A; Polyclonal Antibody; RABBIT ANTI CLOSTRIDIUM DIFFICILE TOXIN A; anti-toxA antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
CLOSTRIDIUM DIFFICILE TOXIN A
This item is specific for Clostridium difficile Toxin A, a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics.
Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
This item is specific for Clostridium difficile Toxin A, a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics.
Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 5.0mg/ml (varies by lot)
Sequence Length
2710
Applicable Applications for anti-toxA antibody
ELISA (EIA)
Perservative Stabilisers
0.09% Sodium Azide (NaN3)
Preparation
Purified IgG prepared by affinity chromatography on Protein G.
Immunogen
Synthetic peptide corresponding to the amino acids 2123 - 2132 of the native molecule conjugated to Keyhole limpet Haemocyanin.Peptide sequence: CTIDGKKYYFN
Buffer Solution
Phosphate buffered saline
Target Species
Bacterial
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-toxA antibody
MBS220533 is specific for Clostridium difficile Toxin A, a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
308,056 Da
NCBI Official Full Name
Toxin A
UniProt Protein Name
Toxin A
Protein Family
UniProt Gene Name
toxA
UniProt Synonym Gene Names
tcdA
UniProt Entry Name
TOXA_PEPDI
Uniprot Description
Only after the enteral delivery of the enterotoxin A may the characteristic disease called pseudomembranous colitis be induced.
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Product Notes
The CLOSTRIDIUM DIFFICILE TOXIN A toxa (Catalog #AAA220533) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CLOSTRIDIUM DIFFICILE TOXIN A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the CLOSTRIDIUM DIFFICILE TOXIN A toxa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLOSTRIDIUM DIFFICILE TOXIN A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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