Western Blot (WB)
(Mouse Clk4 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Clk4 antibody detected the Clk4 protein (arrow).)
Rabbit anti-Mouse Clk4 Polyclonal Antibody | anti-Clk4 antibody
Mouse Clk4 Antibody (N-term)
Western Blot (WB)
(Mouse Clk4 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Clk4 antibody detected the Clk4 protein (arrow).)
Western Blot (WB)
(Mouse Clk4 Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Clk4 antibody detected the Clk4 protein (arrow).)
Hartmann, A.M., et al. Mol. Cell. Neurosci. 18(1):80-90(2001)
Watkins-Chow, D.E., et al. Genomics 45(1):147-157(1997)
Nayler, O., et al. Biochem. J. 326 (PT 3), 693-700 (1997) :
NCBI and Uniprot Product Information
Uniprot Description
CLK4: a CMGC kinase of the CLK family. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. It has been reported to regulate splicing of genes such as Tau exon 10 in the mammalian nervous system. Expressed in liver, kidney, heart, muscle and brain. Clk4 mRNAs were expressed in the hippocampus, the cerebellum, and the olfactory bulb.
Protein type: EC 2.7.12.1; Kinase, protein; Protein kinase, dual-specificity (non-receptor); Protein kinase, CMGC; CMGC group; CLK family
Cellular Component: nucleus
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; protein serine/threonine/tyrosine kinase activity; kinase activity; ATP binding; protein kinase activity
Biological Process: peptidyl-tyrosine phosphorylation; regulation of RNA splicing; protein amino acid autophosphorylation; phosphorylation; protein amino acid phosphorylation
Research Articles on Clk4
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Product Notes
The Clk4 clk4 (Catalog #AAA9205514) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 49-77. The Mouse Clk4 Antibody (N-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Clk4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Clk4 clk4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Clk4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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