Rabbit CLIP3 Polyclonal Antibody | anti-CLIP3 antibody

CLIP3 Antibody

Cat. Num. AAA7116143

• Gene Names: CLIP3; RSNL1; CLIPR59; CLIPR-59
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: CLIP3; Polyclonal Antibody; CLIP3 Antibody; CLIPR59; CAP-Gly domain-containing linker protein 3; Cytoplasmic linker protein 170-related 59 kDa protein; CLIP-170-related 59 kDa protein; CLIPR-59; anti-CLIP3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

• Applicable Applications for anti-CLIP3 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; IHC: 1:100-1:300; IF: 1:200-1:1000; ELISA: 1:40000
• Immunogen: Synthesized peptide derived from the Internal region of human CLIP3.
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of A549 cells using CLIP3 Polyclonal Antibody)

Product Categories/Family for anti-CLIP3 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 313851097
• NCBI GeneID: 25999
• NCBI Accession #: NP_001186499.1
• NCBI GenBank Nucleotide #: NM_001199570.1
• UniProt Accession #: Q96DZ5; Q8WWL1; Q96C99; Q9UFT7; A8K0E4
• Molecular Weight: 59,560 Da
• NCBI Official Full Name: CAP-Gly domain-containing linker protein 3
• NCBI Official Synonym Full Names: CAP-GLY domain containing linker protein 3
• NCBI Official Symbol: CLIP3
• NCBI Official Synonym Symbols: RSNL1; CLIPR59; CLIPR-59
• NCBI Protein Information: CAP-Gly domain-containing linker protein 3; restin-like 1; CLIP-170-related 59 kDa protein; cytoplasmic linker protein 170-related 59 kDa protein
• UniProt Protein Name: CAP-Gly domain-containing linker protein 3
• Protein Family: CAP-Gly domain-containing linker protein
• UniProt Gene Name: CLIP3
• UniProt Synonym Gene Names: CLIPR59; CLIP-170-related 59 kDa protein; CLIPR-59
• UniProt Entry Name: CLIP3_HUMAN

NCBI Description

This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

Uniprot Description

CLIPR-59: Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: Golgi stack; early endosome membrane; recycling endosome membrane; plasma membrane; trans-Golgi network membrane; trans-Golgi network; lipid raft

Molecular Function: microtubule binding

Biological Process: peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine; fat cell differentiation; positive regulation of apoptosis; negative regulation of microtubule polymerization; positive regulation of endocytosis; positive regulation of protein amino acid phosphorylation