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Rabbit anti-Human CLIC2 Polyclonal Antibody | anti-CLIC2 antibody

CLIC2 (Center) Rabbit pAb

Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
CLIC2; Polyclonal Antibody; CLIC2 (Center) Rabbit pAb; Chloride intracellular channel protein 2; XAP121; anti-CLIC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Purity/Purification
Affinity Purified
Form/Format
In PBS supplemented with 0.09% (W/V) Sodium Azide.
Sequence Length
247
Applicable Applications for anti-CLIC2 antibody
Western Blot (WB)
Application Notes
WB: 1:2000
Immunogen
This CLIC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 105-137 amino acids from the central region of human CLIC2.
Cellular Localization
Cytoplasm, Membrane

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
chloride intracellular channel protein 2
UniProt Protein Name
Chloride intracellular channel protein 2
UniProt Gene Name
CLIC2
UniProt Entry Name
CLIC2_HUMAN

Uniprot Description

CLIC2: Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx. Belongs to the chloride channel CLIC family.

Protein type: Channel, chloride; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; intracellular; nucleus

Molecular Function: chloride channel activity; protein binding; glutathione transferase activity; voltage-gated ion channel activity; glutathione peroxidase activity

Biological Process: transport; positive regulation of binding; signal transduction

Disease: Mental Retardation, X-linked, Syndromic 32

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Product Notes

The CLIC2 clic2 (Catalog #AAA8557738) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLIC2 (Center) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLIC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the CLIC2 clic2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLIC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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