Rabbit anti-Human CLEC2B Polyclonal Antibody | anti-CLEC2B antibody

CLEC2B, ID (CLEC2B, AICL, CLECSF2, IFNRG1, C-type lectin domain family 2 member B, Activation-induced C-type lectin, C-type lectin superfamily member 2, IFN-alpha-2b-inducing-related protein 1) (APC)

Cat. Num. AAA6286647

• Gene Names: CLEC2B; AICL; IFNRG1; CLECSF2; HP10085
• Reactivity: Human
• Applications: Western Blot, Flow Cytometry, Functional Assay
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: CLEC2B; Polyclonal Antibody; ID (CLEC2B; AICL; CLECSF2; IFNRG1; C-type lectin domain family 2 member B; Activation-induced C-type lectin; C-type lectin superfamily member 2; IFN-alpha-2b-inducing-related protein 1) (APC); IFN-alpha-2b-inducing-related protein 1; anti-CLEC2B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CLEC2B.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-CLEC2B antibody: Western Blot (WB), Flow Cytometry (FC/FACS), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 59-86 in the central region of human CLEC2B.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of Hela cell line lysates (35ug/lane) usingMBS641127. This demonstrates that MBS641127 detected the CLEC2B protein (arrow).)

Flow Cytometry (FC/FACS)

(Flow Cytometric analysis of Hela cells using 033981(right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-CLEC2B antibody

CLEC2B encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen.

Product Categories/Family for anti-CLEC2B antibody

Antibodies; Lectins

References

1. Kuttruff, S., et al. Blood 113(2):358-369(2009). 2. Ebner, S., et al. Proteins 53(1):44-55(2003). 3. Renedo, M., et al. Genomics 65(2):129-136(2000).

NCBI and Uniprot Product Information

• NCBI GI #: 37577107
• NCBI GeneID: 9976
• NCBI Accession #: NP_005118.2
• NCBI GenBank Nucleotide #: NM_005127.2
• UniProt Accession #: Q92478; Q8IZE9; Q9BS74; Q9UQB4; B2R9U1
• Molecular Weight: 17,307 Da
• NCBI Official Full Name: C-type lectin domain family 2 member B
• NCBI Official Synonym Full Names: C-type lectin domain family 2 member B
• NCBI Official Symbol: CLEC2B
• NCBI Official Synonym Symbols: AICL; IFNRG1; CLECSF2; HP10085
• NCBI Protein Information: C-type lectin domain family 2 member B
• UniProt Protein Name: C-type lectin domain family 2 member B
• Protein Family: C-type lectin domain family
• UniProt Gene Name: CLEC2B
• UniProt Synonym Gene Names: AICL; CLECSF2; IFNRG1
• UniProt Entry Name: CLC2B_HUMAN

Uniprot Description

CLEC2B:

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13-p12

Cellular Component: integral to plasma membrane; plasma membrane

Biological Process: regulation of immune response