Rabbit anti-Human CLEC2A Polyclonal Antibody | anti-CLEC2A antibody
CLEC2A Antibody
Gene Names
CLEC2A; KACL; PILAR; UNQ5792; INPE5792
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
CLEC2A; Polyclonal Antibody; CLEC2A Antibody; C-type lectin domain family 2 member A; CLC2A_HUMAN; INPE5792; KACL; Keratinocyte-associated C-type lectin; PILAR; Proliferation-induced lymphocyte-associated receptor; UNQ5792; anti-CLEC2A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
CLEC2A Antibody detects endogenous levels of CLEC2A.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CLEC2A antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human CLEC2A.
Conjugation
Unconjugated
Post Translational Modifications
N-glycosylated.
Subunit Structure
Homodimer; non disulfide-linked. Interacts with KLRB1. Interacts with KLRF2.
Tissue Specificity
Mainly expressed in skin. Also expressed in keratinocytes, spleen, thymus, small intestine, peripheral blood monocytes, bone marrow, ovary, testis and skin. High expression in CD8(+), B-lymphocytes and naive CD4(+) T-cells. Restricted mostly to proliferating lymphocytes. Not detected in myeloid leukocytes or natural killer (NK) cells.
Function
Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti-apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-CLEC2A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
174
NCBI Official Full Name
C-type lectin domain family 2 member A
NCBI Official Synonym Full Names
C-type lectin domain family 2, member A
NCBI Official Symbol
CLEC2A
NCBI Official Synonym Symbols
KACL; PILAR; UNQ5792; INPE5792
NCBI Protein Information
C-type lectin domain family 2 member A; keratinocyte-associated C-type lectin; proliferation-induced lymphocyte-associated receptor
UniProt Protein Name
C-type lectin domain family 2 member A
Protein Family
UniProt Gene Name
CLEC2A
UniProt Synonym Gene Names
KACL; KACL; PILAR
UniProt Entry Name
CLC2A_HUMAN
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Product Notes
The CLEC2A clec2a (Catalog #AAA9631050) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLEC2A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLEC2A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the CLEC2A clec2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLEC2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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