Western Blot (WB)
(All lanes : Anti-CLEC1B Antibody (N-Term) at dilutionLane 1: HepG2 whole cell lysateLane 2: U266B1 whole cell lysateLane 3: 293 whole cell lysateLane 4: Human testis lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 27kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human CLEC1B Polyclonal Antibody | anti-CLEC1B antibody
CLEC1B Antibody (N-Term)
Gene Names
CLEC1B; CLEC2; CLEC2B; PRO1384; QDED721; 1810061I13Rik
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified through a protein A column, followed by peptide affinity purification.
Synonyms
CLEC1B; Polyclonal Antibody; CLEC1B Antibody (N-Term); Purified Rabbit Polyclonal Antibody (Pab); C-type lectin domain family 1 member B; C-type lectin-like receptor 2; CLEC-2; CLEC2; anti-CLEC1B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Specificity
This CLEC1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-78 amino acids from the human region of human CLEC1B.
Purity/Purification
Purified through a protein A column, followed by peptide affinity purification.
Form/Format
Supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Length
196
Applicable Applications for anti-CLEC1B antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:2000
Antigen Type
Synthesized Peptide
Antigen Source
Human
Tissue Location
Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
Cellular Location
Membrane; Single-pass type II membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks.
For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(All lanes : Anti-CLEC1B Antibody (N-Term) at dilutionLane 1: HepG2 whole cell lysateLane 2: U266B1 whole cell lysateLane 3: 293 whole cell lysateLane 4: Human testis lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 27kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-CLEC1B Antibody (N-Term) at dilutionLane 1: HepG2 whole cell lysateLane 2: U266B1 whole cell lysateLane 3: 293 whole cell lysateLane 4: Human testis lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 27kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Product Categories/Family for anti-CLEC1B antibody
References
Colonna M.,et al.Eur. J. Immunol. 30:697-704(2000). Chaipan C.,et al.J. Virol. 80:8951-8960(2006). Clark H.F.,et al.Genome Res. 13:2265-2270(2003). Scherer S.E.,et al.Nature 440:346-351(2006). Suzuki-Inoue K.,et al.Blood 107:542-549(2006).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26596
NCBI Official Full Name
C-type lectin domain family 1 member B isoform b
NCBI Official Synonym Full Names
C-type lectin domain family 1 member B
NCBI Official Symbol
CLEC1B
NCBI Official Synonym Symbols
CLEC2; CLEC2B; PRO1384; QDED721; 1810061I13Rik
NCBI Protein Information
C-type lectin domain family 1 member B
UniProt Protein Name
C-type lectin domain family 1 member B
Protein Family
UniProt Gene Name
CLEC1B
UniProt Synonym Gene Names
CLEC2; CLEC-2
NCBI Description
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
Uniprot Description
C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN (PubMed:18215137). After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2 (PubMed:18955485).
Research Articles on CLEC1B
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Product Notes
The CLEC1B clec1b (Catalog #AAA9231244) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLEC1B Antibody (N-Term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLEC1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:2000. Researchers should empirically determine the suitability of the CLEC1B clec1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLEC1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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