Western Blot (WB)
(Western blot analysis of CLEC11A (arrow) using rabbit polyclonal CLEC11A Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLEC11A gene.)
Rabbit anti-Human CLEC11A Polyclonal Antibody | anti-CLEC11A antibody
CLEC11A Antibody (Center)
Western Blot (WB)
(Western blot analysis of CLEC11A (arrow) using rabbit polyclonal CLEC11A Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLEC11A gene.)
Western Blot (WB)
(Western blot analysis of CLEC11A (arrow) using rabbit polyclonal CLEC11A Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CLEC11A gene.)
Immunohistochemistry (IHC)
(CLEC11A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLEC11A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CLEC11A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLEC11A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(CLEC11A Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(CLEC11A Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
superfamily. The encoded protein is a secreted sulfated
glycoprotein and functions as a growth factor for primitive
hematopoietic progenitor cells. An alternative splice variant has
been described but its biological nature has not been determined.
Keller, C.C., et al. Infect. Immun. 77(9):3864-3871(2009)
Lan, C.C., et al. Br. J. Dermatol. 160(6):1180-1187(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hollenbeck, S.T., et al. J. Surg. Res. 120(2):288-294(2004)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
CLEC11A: Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: extracellular space; cytoplasm; extracellular region
Molecular Function: growth factor activity; carbohydrate binding
Biological Process: positive regulation of cell proliferation
Research Articles on CLEC11A
Similar Products
Product Notes
The CLEC11A clec11a (Catalog #AAA9201565) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 145-174. The CLEC11A Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLEC11A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the CLEC11A clec11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLEC11A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
