Rabbit anti-Human CLDN20 Polyclonal Antibody | anti-CLDN20 antibody

CLDN20 Antibody

Cat. Num. AAA7005963

• Reactivity: Human
• Applications: ELISA, Western Blot, Immunofluorescence
• Purity: >95%,Protein G purified
• Synonyms: CLDN20; Polyclonal Antibody; CLDN20 Antibody; Claudin-20; anti-CLDN20 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 219

• Applicable Applications for anti-CLDN20 antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
• Immunogen: Recombinant human Claudin-20 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western blotAll lanes: CLDN20 antibody at 4ug/mlLane 1: A549 whole cell lysateLane 2: HepG-2 whole cell lysateLane 3: PC-3 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 24 kDaObserved band size: 24 kDa)

Immunofluorescence (IF)

(Immunofluorescent analysis of HepG2 cells using MBS7005963 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-CLDN20 antibody

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

NCBI and Uniprot Product Information

• NCBI GI #: 47716519
• NCBI GeneID: 49861
• NCBI Accession #: NP_001001346.1
• NCBI GenBank Nucleotide #: NM_001001346.3
• UniProt Accession #: P56880
• Molecular Weight: 23,515 Da
• NCBI Official Full Name: claudin-20
• NCBI Official Synonym Full Names: claudin 20
• NCBI Official Symbol: CLDN20
• NCBI Protein Information: claudin-20
• UniProt Protein Name: Claudin-20
• Protein Family: Claudin
• UniProt Gene Name: CLDN20
• UniProt Entry Name: CLD20_HUMAN

NCBI Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. [provided by RefSeq, Jun 2010]

Uniprot Description

Claudin-20: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion

Chromosomal Location of Human Ortholog: 6q25

Cellular Component: integral to membrane; plasma membrane; tight junction

Molecular Function: identical protein binding; structural molecule activity

Biological Process: calcium-independent cell-cell adhesion; intercellular junction assembly and maintenance