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Goat anti-Human CK1 delta Polyclonal Antibody | anti-CK1 delta antibody

CK1 delta antibody

Gene Names
CSNK1D; ASPS; HCKID; FASPS2; CKIdelta
Reactivity
Human
Applications
Western Blot
Synonyms
CK1 delta; Polyclonal Antibody; CK1 delta antibody; Polyclonal CK1 delta; Anti-CK1 delta; CK-1; CK1 delta C-terminus; Casein Kinase 1 delta; HCKI delta; CSNK1 delta; CK 1; CK1; anti-CK1 delta antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Form/Format
Supplied as serum.
Sequence Length
415
Applicable Applications for anti-CK1 delta antibody
Western Blot (WB)
Application Notes
WB: 1:500
Biological Significance
The casein kinase 1 (CK1) family of protein kinases is common to all eukaryotic cells, with at least 15 sequence-distinct isoforms currently known. Although the isoforms differ in tissue distribution and subcellular localization, CK1 kinases share several characteristics in that they exhibit Ser/Thr-specific protein kinase activity. CK1-Delta has been implicated in the regulation of the tumor suppressor p53 and binds to microtubules, which suggests a regulatory role in mitosis.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
CK1 delta antibody was raised in goat using residues 310-327 of human casein kinase 1d located at the C-terminus as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-CK1 delta antibody
Goat polyclonal CK1 delta antibody
Product Categories/Family for anti-CK1 delta antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,832 Da
NCBI Official Full Name
casein kinase I isoform delta isoform 1
NCBI Official Synonym Full Names
casein kinase 1, delta
NCBI Official Symbol
CSNK1D
NCBI Official Synonym Symbols
ASPS; HCKID; FASPS2; CKIdelta
NCBI Protein Information
casein kinase I isoform delta
UniProt Protein Name
Casein kinase I isoform delta
UniProt Gene Name
CSNK1D
UniProt Synonym Gene Names
HCKID; CKI-delta; CKId
UniProt Entry Name
KC1D_HUMAN

NCBI Description

This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]

Uniprot Description

CK1D: an ubiquitous protein kinase of the CK1 family. Enriched at the centrosomes in interphase and at the spindle during mitosis. May play a role in cell cycle progression. Two splice variant isoforms have been described.

Protein type: EC 2.7.11.26; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CK1; EC 2.7.11.1; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: Golgi apparatus; centrosome; perinuclear region of cytoplasm; spindle microtubule; plasma membrane; spindle; cytosol; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; tau-protein kinase activity; phosphoprotein binding; glycoprotein binding; peptide binding; ATP binding; protein kinase activity

Biological Process: Wnt receptor signaling pathway; organelle organization and biogenesis; endocytosis; spindle assembly; regulation of circadian rhythm; signal transduction; DNA repair; protein amino acid phosphorylation; regulation of cell shape; peptidyl-serine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; mitotic cell cycle; positive regulation of protein amino acid phosphorylation; circadian regulation of gene expression; G2/M transition of mitotic cell cycle

Disease: Advanced Sleep Phase Syndrome, Familial, 2

Research Articles on CK1 delta

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Product Notes

The CK1 delta csnk1d (Catalog #AAA536163) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The CK1 delta antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CK1 delta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500. Researchers should empirically determine the suitability of the CK1 delta csnk1d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CK1 delta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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