Rabbit anti-Human, Mouse CIB4 Polyclonal Antibody | anti-CIB4 antibody

CIB4, NT (CIB4, Calcium and integrin-binding family member 4) (Biotin)

Cat. Num. AAA6286142

• Gene Names: CIB4; KIP4
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CIB4; Polyclonal Antibody; NT (CIB4; Calcium and integrin-binding family member 4) (Biotin); Calcium and integrin-binding family member 4; anti-CIB4 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-CIB4 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: CIB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human CIB4.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CIB4 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the CIB4 antibody detected the CIB4 protein (arrow).)

Western Blot (WB)

(CIB4 Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the CIB4 antibody detected the CIB4 protein (arrow).)

Immunohistochemistry (IHC)

(CIB4 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CIB4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-CIB4 antibody

The exact functions of this protein remain unknown.

Product Categories/Family for anti-CIB4 antibody

Antibodies; Integrin

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Gentry, H.R., et al. J. Biol. Chem. 280(9):8407-8415(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 71274156
• NCBI GeneID: 130106
• NCBI Accession #: NP_001025052.1
• NCBI GenBank Nucleotide #: NM_001029881.1
• UniProt Accession #: A0PJX0; B2RU18
• Molecular Weight: 21,745 Da
• NCBI Official Full Name: calcium and integrin-binding family member 4
• NCBI Official Synonym Full Names: calcium and integrin binding family member 4
• NCBI Official Symbol: CIB4
• NCBI Official Synonym Symbols: KIP4
• NCBI Protein Information: calcium and integrin-binding family member 4
• UniProt Protein Name: Calcium and integrin-binding family member 4
• Protein Family: Calcium and integrin-binding family
• UniProt Gene Name: CIB4
• UniProt Entry Name: CIB4_HUMAN

Uniprot Description

CIB4: Interacts with ITGA2B (via C-terminus cytoplasmic tail region); the interaction is stabilized/increased in a calcium- and magnesium-dependent manner

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 2p23.3

Molecular Function: calcium ion binding