Western Blot (WB)
(CIAPIN1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CIAPIN1 antibody detected the CIAPIN1 protein (arrow).)
Rabbit anti-Human CIAPIN1 Polyclonal Antibody | anti-ciapin1 antibody
CIAPIN1, ID (CIAPIN1, Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(CIAPIN1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CIAPIN1 antibody detected the CIAPIN1 protein (arrow).)
Western Blot (WB)
(CIAPIN1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CIAPIN1 antibody detected the CIAPIN1 protein (arrow).)
NCBI and Uniprot Product Information
Uniprot Description
Function: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein ndor1
By similarity. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells
By similarity. HAMAP-Rule MF_03115
Cofactor: Binds 1 2Fe-2S cluster per subunit
By similarity. HAMAP-Rule MF_03115
Subunit structure: Monomer
By similarity. Interacts with ndor1
By similarity. Interacts with chchd4
By similarity. HAMAP-Rule MF_03115
Subcellular location: Cytoplasm
By similarity. Nucleus
By similarity. Mitochondrion intermembrane space
By similarity HAMAP-Rule MF_03115.
Domain: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine
By similarity. HAMAP-Rule MF_03115The C-terminal domain binds one 2Fe-2S iron-sulfur cluster but is otherwise mostly in an intrinsically disordered conformation
By similarity. HAMAP-Rule MF_03115The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space
By similarity. HAMAP-Rule MF_03115
Sequence similarities: Belongs to the anamorsin family.
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Product Notes
The ciapin1 ciapin1 (Catalog #AAA643937) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CIAPIN1, ID (CIAPIN1, Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CIAPIN1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the ciapin1 ciapin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CIAPIN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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