Western Blot (WB)
(Western Blot:Sample: Recombinant CMA1, Mouse)
Rabbit Chymase 1, Mast Cell (CMA1) Polyclonal Antibody | anti-CMA1 antibody
Polyclonal Antibody to Chymase 1, Mast Cell (CMA1)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot:Sample: Recombinant CMA1, Mouse)
Western Blot (WB)
(Western Blot:Sample: Recombinant CMA1, Mouse)
Immunohistochemistry (IHC)
(Used in DAB staining on fromalin fixed paraffin- embedded brain tissue)
Immunohistochemistry (IHC)
(Used in DAB staining on fromalin fixed paraffin- embedded brain tissue)
Western Blot (WB)
(Western Blot:Sample:Lane1: Mouse Large Intestine Tissue;Lane2: Mouse Testis Tissue;Lane3: Human PC-3 Cells)
Western Blot (WB)
(Western Blot:Sample:Lane1: Mouse Large Intestine Tissue;Lane2: Mouse Testis Tissue;Lane3: Human PC-3 Cells)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Lung Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Lung Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Uterine Fibroids Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Mouse Uterine Fibroids Tissue)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a serine protease that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. The encoded preproprotein undergoes proteolytic processing to generate a functional enzyme with elastase-like activity. Mice lacking the encoded protein exhibit significant attenuation of ischemia-reperfusion injury of the skeletal muscle. This gene is located in a cluster of related mast cell protease genes on chromosome 14. [provided by RefSeq, Nov 2015]
Uniprot Description
CMA1: Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. Belongs to the peptidase S1 family. Granzyme subfamily.
Protein type: EC 3.4.21.39; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 14 C3|14 28.19 cM
Cellular Component: extracellular matrix; extracellular region; intracellular; secretory granule
Molecular Function: endopeptidase activity; hydrolase activity; peptidase activity; peptide binding; serine-type endopeptidase activity; serine-type peptidase activity
Biological Process: interleukin-1 beta biosynthetic process; positive regulation of angiogenesis; proteolysis
Research Articles on CMA1
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Product Notes
The CMA1 cma1 (Catalog #AAA2002348) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Chymase 1, Mast Cell (CMA1) reacts with Mus musculus (Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's Chymase 1, Mast Cell (CMA1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the CMA1 cma1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Chymase 1, Mast Cell (CMA1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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