Western Blot (WB)
(Western Blot analysis of CHKA expression in transfected 293T cell line by CHKA polyclonal antibody. Lane 1: CHKA transfected lysate (52.2kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human CHK Polyclonal Antibody | anti-CHK antibody
CHK (Choline Kinase alpha, CK, CHETK-alpha, Ethanolamine Kinase, EK, CHKA, CKI) (AP)
Western Blot (WB)
(Western Blot analysis of CHKA expression in transfected 293T cell line by CHKA polyclonal antibody. Lane 1: CHKA transfected lysate (52.2kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CHKA expression in transfected 293T cell line by CHKA polyclonal antibody. Lane 1: CHKA transfected lysate (52.2kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
CHKA: Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. Belongs to the choline/ethanolamine kinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - glycerophospholipid; EC 2.7.1.82; Kinase, other; EC 2.7.1.32
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: cytosol
Molecular Function: choline binding; signal transducer activity; protein homodimerization activity; cholinesterase activity; drug binding; ethanolamine kinase activity; choline kinase activity; ATP binding
Biological Process: choline metabolic process; CDP-choline pathway; phospholipid metabolic process; glycerophospholipid biosynthetic process; phosphatidylethanolamine biosynthetic process; phosphatidylcholine biosynthetic process; lipid metabolic process; signal transduction; lipid transport; phosphorylation
Research Articles on CHK
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Product Notes
The CHK chka (Catalog #AAA6373873) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHK (Choline Kinase alpha, CK, CHETK-alpha, Ethanolamine Kinase, EK, CHKA, CKI) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CHK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CHK chka for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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