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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gastric using CHIC2 antibody at dilution of 1:100 (x40 lens).)

Rabbit CHIC2 Polyclonal Antibody | anti-CHIC2 antibody

CHIC2 Polyclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CHIC2; Polyclonal Antibody; CHIC2 Polyclonal Antibody; BTL; BrX-like translocated in leukemia; anti-CHIC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CHIC2 polyclonal antibody detects endogenous levels of CHIC2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
165
Applicable Applications for anti-CHIC2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
Recombinant protein of human CHIC2.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gastric using CHIC2 antibody at dilution of 1:100 (x40 lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gastric using CHIC2 antibody at dilution of 1:100 (x40 lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat brain using CHIC2 antibody at dilution of 1:100 (x40 lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat brain using CHIC2 antibody at dilution of 1:100 (x40 lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse brain using CHIC2 antibody at dilution of 1:100 (x40 lens).)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse brain using CHIC2 antibody at dilution of 1:100 (x40 lens).)
Related Product Information for anti-CHIC2 antibody
This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 19kDa
NCBI Official Full Name
cysteine-rich hydrophobic domain-containing protein 2
UniProt Protein Name
Cysteine-rich hydrophobic domain 2 protein
UniProt Gene Name
CHIC2
UniProt Synonym Gene Names
BTL
UniProt Entry Name
CHIC2_HUMAN

Uniprot Description

Subcellular location: Cell membrane. Cytoplasmic vesicle. Note: Also present at a Golgi-like vesicular compartment and at scattered vesicles. Ref.5

Post-translational modification: Palmitoylation in the CHIC motif is required for membrane association. Ref.5

Involvement in disease: A chromosomal aberration involving CHIC2 is found in a form of acute myeloid leukemia (AML). Translocation t(4;12)(q12;p13) with ETV6.

Sequence similarities: Belongs to the CHIC family.

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Product Notes

The CHIC2 chic2 (Catalog #AAA3008976) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CHIC2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CHIC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CHIC2 chic2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHIC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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