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Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CES4A Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))

Rabbit anti-Human CES4A Polyclonal Antibody | anti-CES4A antibody

CES4A Antibody

Gene Names
CES4A; CES6; CES8
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
CES4A; Polyclonal Antibody; CES4A Antibody; CES6; CES8; anti-CES4A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CES4A protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.5mg/ml (varies by lot)
Sequence Length
463
Applicable Applications for anti-CES4A antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1: 20-100
Immunogen
Synthetic peptide of human CES4A
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CES4A Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CES4A Antibody at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-CES4A antibody
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined.
Product Categories/Family for anti-CES4A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,504 Da
NCBI Official Full Name
carboxylesterase 4A isoform 3
NCBI Official Synonym Full Names
carboxylesterase 4A
NCBI Official Symbol
CES4A
NCBI Official Synonym Symbols
CES6; CES8
NCBI Protein Information
carboxylesterase 4A
UniProt Protein Name
Carboxylesterase 4A
Protein Family
UniProt Gene Name
CES4A
UniProt Synonym Gene Names
CES8
UniProt Entry Name
EST4A_HUMAN

NCBI Description

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES6, encodes a secreted enzyme, and may play a role in the detoxification of drugs and xenobiotics in neural and other tissues of the body and in the cerebrospinal fluid. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature and/or biological validity of some variants have not been determined. [provided by RefSeq, Jun 2010]

Uniprot Description

CES8: Probable carboxylesterase. Belongs to the type-B carboxylesterase/lipase family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.1.-; Hydrolase

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: extracellular space

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Product Notes

The CES4A ces4a (Catalog #AAA9417342) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CES4A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CES4A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1: 20-100. Researchers should empirically determine the suitability of the CES4A ces4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CES4A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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