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Western Blot (WB) (ELA3A rabbit polyclonal antibody. Western Blot analysis of ELA3A expression in human pancreas.)

Rabbit anti-Human CELA3A Polyclonal Antibody | anti-CELA3A antibody

CELA3A (ELA3, ELA3A, Chymotrypsin-like Elastase Family Member 3A, Elastase IIIA, Elastase-3A, Protease E)

Gene Names
CELA3A; ELA3; ELA3A
Reactivity
Human
Applications
Western Blot, Immunoprecipitation
Purity
Serum
Serum
Synonyms
CELA3A; Polyclonal Antibody; CELA3A (ELA3; ELA3A; Chymotrypsin-like Elastase Family Member 3A; Elastase IIIA; Elastase-3A; Protease E); Anti -CELA3A (ELA3; anti-CELA3A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ELA3A.
Purity/Purification
Serum
Serum
Form/Format
Supplied as a liquid.
Sequence
MMLRLLSSLLLVAVASGYGPPSSHSSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISRDLTYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNGPLPDKLQQARLPVVDYKHCSRWNWWGSTVKKTMVCAGGYIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSGFGCNFIWKPTVFTRVSAFIDWIEETIASH
Applicable Applications for anti-CELA3A antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
Suitable for use in Immunoprecipitation and Western Blot.
Immunogen
Full-length human ELA3A, aa1-270 (NP_005738.3).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ELA3A rabbit polyclonal antibody. Western Blot analysis of ELA3A expression in human pancreas.)

Western Blot (WB) (ELA3A rabbit polyclonal antibody. Western Blot analysis of ELA3A expression in human pancreas.)

Western Blot (WB)

(Western Blot analysis of ELA3A expression in transfected 293T cell line by ELA3A polyclonal antibody. Lane 1: ELA3A transfected lysate (29.5kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of ELA3A expression in transfected 293T cell line by ELA3A polyclonal antibody. Lane 1: ELA3A transfected lysate (29.5kD). Lane 2: Non-transfected lysate.)

Immunoprecipitation (IP)

(Immunoprecipitation of ELA3A transfected lysate using ELA3A rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ELA3A mouse polyclonal antibody.)

Immunoprecipitation (IP) (Immunoprecipitation of ELA3A transfected lysate using ELA3A rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ELA3A mouse polyclonal antibody.)
Related Product Information for anti-CELA3A antibody
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1.
Product Categories/Family for anti-CELA3A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29,489 Da
NCBI Official Full Name
chymotrypsin-like elastase family member 3A preproprotein
NCBI Official Synonym Full Names
chymotrypsin-like elastase family, member 3A
NCBI Official Symbol
CELA3A
NCBI Official Synonym Symbols
ELA3; ELA3A
NCBI Protein Information
chymotrypsin-like elastase family member 3A; elastase 1; protease E; elastase-3A; elastase IIIA; elastase 3A, pancreatic
UniProt Protein Name
Chymotrypsin-like elastase family member 3A
UniProt Gene Name
CELA3A
UniProt Synonym Gene Names
ELA3; ELA3A
UniProt Entry Name
CEL3A_HUMAN

NCBI Description

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. [provided by RefSeq, Jul 2008]

Uniprot Description

CELA3A: Efficient protease with alanine specificity but only little elastolytic activity. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: EC 3.4.21.70; Protease

Chromosomal Location of Human Ortholog: 1p36.12

Molecular Function: serine-type endopeptidase activity

Biological Process: cholesterol metabolic process; digestion; proteolysis

Research Articles on CELA3A

Similar Products

Product Notes

The CELA3A cela3a (Catalog #AAA641363) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CELA3A (ELA3, ELA3A, Chymotrypsin-like Elastase Family Member 3A, Elastase IIIA, Elastase-3A, Protease E) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CELA3A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). Suitable for use in Immunoprecipitation and Western Blot. Researchers should empirically determine the suitability of the CELA3A cela3a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MMLRLLSSLL LVAVASGYGP PSSHSSSRVV HGEDAVPYSW PWQVSLQYEK SGSFYHTCGG SLIAPDWVVT AGHCISRDLT YQVVLGEYNL AVKEGPEQVI PINSEELFVH PLWNRSCVAC GNDIALIKLS RSAQLGDAVQ LASLPPAGDI LPNKTPCYIT GWGRLYTNGP LPDKLQQARL PVVDYKHCSR WNWWGSTVKK TMVCAGGYIR SGCNGDSGGP LNCPTEDGGW QVHGVTSFVS GFGCNFIWKP TVFTRVSAFI DWIEETIASH. It is sometimes possible for the material contained within the vial of "CELA3A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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