Rabbit anti-Human CECR5 Polyclonal Antibody | anti-CECR5 antibody

CECR5 Antibody

Cat. Num. AAA9429612

• Gene Names: HDHD5; CECR5
• Reactivity: Human
• Applications: Western Blot
• Purity: Antigen affinity purification
• Synonyms: CECR5; Polyclonal Antibody; CECR5 Antibody; anti-CECR5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: The antibody detects endogenous levels of total CECR5 protein.
• Purity/Purification: Antigen affinity purification
• Form/Format: In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 1.7mg/ml (varies by lot)
• Sequence Length: 423

• Applicable Applications for anti-CECR5 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Synthetic peptide corresponding to residues near the C terminal of human CECR5
• Immunogen Type: Peptide
• Preparation and Storage: Store at -20 degree C.

SDS-Page

(Gel: 8%SDS-PAGE, Lysate: 40 ¦Œg, , Lane 1-5: Jurkat, HEPG2 and Hela cell, Human testis tissue, 231 cell lysates, Primary antibody: 46465(CECR5 Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds)

Related Product Information for anti-CECR5 antibody

Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.

Product Categories/Family for anti-CECR5 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 14861834
• NCBI GeneID: 27440
• NCBI Accession #: NP_149061
• NCBI GenBank Nucleotide #: NM_033070.2
• UniProt Accession #: Q9BXW7; Q9BXW8; Q9NWA8; Q9NX41; B2RCK5
• Molecular Weight: 46 kDa
• NCBI Official Full Name: haloacid dehalogenase-like hydrolase domain-containing 5 isoform 2
• NCBI Official Synonym Full Names: haloacid dehalogenase like hydrolase domain containing 5
• NCBI Official Symbol: HDHD5
• NCBI Official Synonym Symbols: CECR5
• NCBI Protein Information: haloacid dehalogenase-like hydrolase domain-containing 5; cat eye syndrome critical region protein 5
• UniProt Protein Name: Haloacid dehalogenase-like hydrolase domain-containing 5
• Protein Family: Cat eye syndrome critical region protein
• UniProt Gene Name: HDHD5

Uniprot Description

MiscellaneousCandidate gene for the Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. Duplication usually takes in the form of a surpernumerary bisatellited isodicentric chromosome, resulting in four copies of the region (represents an inv dup(22)(q11)). CES is characterized clinically by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development.