Rabbit anti-Human, Mouse CEBPG Polyclonal Antibody | anti-CEBPG antibody

CEBPG, CT (CEBPG, CCAAT/enhancer-binding protein gamma) (APC)

Cat. Num. AAA6284975

• Gene Names: CEBPG; GPE1BP; IG/EBP-1
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CEBPG; Polyclonal Antibody; CT (CEBPG; CCAAT/enhancer-binding protein gamma) (APC); CCAAT/enhancer-binding protein gamma; anti-CEBPG antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-CEBPG antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CEBPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-110 amino acids from the C-terminal region of human CEBPG.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(CEBPG Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the CEBPG antibody detected the CEBPG protein (arrow).)

Product Categories/Family for anti-CEBPG antibody

Antibodies; Binding Proteins

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010). Crawford, E.L., et al. Carcinogenesis 28(12):2552-2559(2007). Mullins, D.N., et al. BMC Cancer 5, 141 (2005): Newman, J.R., et al. Science 300(5628):2097-2101(2003). Hattori, T., et al. Oncogene 22(9):1273-1280(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 4502769
• NCBI GeneID: 1054
• NCBI Accession #: NP_001797.1
• NCBI GenBank Nucleotide #: NM_001806.3
• UniProt Accession #: P53567; Q5U052; B2R946
• Molecular Weight: 16,408 Da
• NCBI Official Full Name: CCAAT/enhancer-binding protein gamma
• NCBI Official Synonym Full Names: CCAAT/enhancer binding protein (C/EBP), gamma
• NCBI Official Symbol: CEBPG
• NCBI Official Synonym Symbols: GPE1BP; IG/EBP-1
• NCBI Protein Information: CCAAT/enhancer-binding protein gamma; c/EBP gamma
• UniProt Protein Name: CCAAT/enhancer-binding protein gamma
• Protein Family: CCAAT/enhancer-binding protein
• UniProt Gene Name: CEBPG
• UniProt Synonym Gene Names: C/EBP gamma
• UniProt Entry Name: CEBPG_HUMAN

NCBI Description

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

C/EBP-gamma: Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites. Belongs to the bZIP family. C/EBP subfamily.

Protein type: Transcription factor; Motility/polarity/chemotaxis; DNA-binding

Chromosomal Location of Human Ortholog: 19q13.11

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; double-stranded DNA binding; transcription factor binding

Biological Process: positive regulation of DNA repair; transcription, DNA-dependent; natural killer cell mediated cytotoxicity; negative regulation of transcription factor activity; enucleate erythrocyte differentiation; liver development; mRNA metabolic process; regulation of transcription from RNA polymerase II promoter; B cell differentiation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; immune response; positive regulation of interferon-gamma biosynthetic process; positive regulation of DNA binding