Western Blot (WB)
(CDY1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CDY1 antibody detected the CDY1 protein (arrow).)
Rabbit anti-Human CDY1 Polyclonal Antibody | anti-CDY1 antibody
CDY1 Antibody (N-term)
Western Blot (WB)
(CDY1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CDY1 antibody detected the CDY1 protein (arrow).)
Western Blot (WB)
(CDY1 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CDY1 antibody detected the CDY1 protein (arrow).)
a histone acetyltransferase catalytic domain. Chromodomain proteins
are components of heterochromatin-like complexes and can act as
gene repressors. This protein is localized to the nucleus of late
spermatids where histone hyperacetylation takes place. Histone
hyperacetylation is thought to facilitate the transition in which
protamines replace histones as the major DNA-packaging protein. The
human chromosome Y has two identical copies of this gene within a
palindromic region; this record represents the more centromeric
copy. Chromosome Y also contains a pair of closely related genes in
another more telomeric palindrome as well as several related
pseudogenes. Two protein isoforms are encoded by transcript
variants of this gene. Additional transcript variants have been
described, but their full-length nature has not been determined.
Dorus, S., et al. Hum. Mol. Genet. 12(14):1643-1650(2003)
Skaletsky, H., et al. Nature 423(6942):825-837(2003)
Lahn, B.T., et al. Proc. Natl. Acad. Sci. U.S.A. 99(13):8707-8712(2002)
Ferlin, A., et al. J. Endocrinol. Invest. 24 (2), RC4-RC6 (2001) :
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
CDY1: Has histone acetyltransferase activity, with a preference for histone H4. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.3.1.48; Acetyltransferase
Chromosomal Location of Human Ortholog: Yq11.23
Cellular Component: nucleus
Molecular Function: histone acetyltransferase activity; methylated histone residue binding
Biological Process: spermatogenesis; histone acetylation
Disease: Spermatogenic Failure, Y-linked, 2
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Product Notes
The CDY1 cdy1 (Catalog #AAA9206785) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The CDY1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDY1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CDY1 cdy1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDY1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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