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Western Blot (WB) (Anti-Mouse Cdk13 Antibody (N-term) at 1:1000 dilution + mouse testis lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 165 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Mouse Cdk13 Polyclonal Antibody | anti-Cdk13 antibody

Mouse Cdk13 Antibody (N-term)

Gene Names
Cdk13; Cdc2l5; 2310015O17Rik
Reactivity
Mouse
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Cdk13; Polyclonal Antibody; Mouse Cdk13 Antibody (N-term); Cyclin-dependent kinase 13; CDC2-related protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; Cdc2l5; Kiaa1791; anti-Cdk13 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Cdk13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the N-terminal region of mouse Cdk13.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
282-310
Sequence Length
1,451
Applicable Applications for anti-Cdk13 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Function
Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis.
Cellular location
Nucleus speckle
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-Mouse Cdk13 Antibody (N-term) at 1:1000 dilution + mouse testis lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 165 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-Mouse Cdk13 Antibody (N-term) at 1:1000 dilution + mouse testis lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 165 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-Cdk13 antibody
Cdk13 may be a controller of the mitotic cell cycle. Involved in the blood cell development (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
cyclin-dependent kinase 13 isoform 1
NCBI Official Synonym Full Names
cyclin-dependent kinase 13
NCBI Official Symbol
Cdk13
NCBI Official Synonym Symbols
Cdc2l5; 2310015O17Rik
NCBI Protein Information
cyclin-dependent kinase 13
UniProt Protein Name
Cyclin-dependent kinase 13
Protein Family
UniProt Gene Name
Cdk13
UniProt Synonym Gene Names
Cdc2l5; Kiaa1791
UniProt Entry Name
CDK13_MOUSE

Uniprot Description

CDK13: a CMGC protein kinase of the CDK family. It has been reported to interact with L-type cyclins. Overexpression of CDC2L5 constructs disturbs constitutive splicing and switches alternative splice site selection in vivo suggesting that it may regulate alternative splicing. It has unusually large N- and C-termini and is ubiquitously expressed in many tissues. Two alternatively spliced human isoforms have been described.

Protein type: Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; RNA splicing; EC 2.7.11.23; Kinase, protein; EC 2.7.11.22; Cell cycle regulation; CMGC group; CDK family; CRK7 subfamily; CDK/CRK7 subfamily

Cellular Component: nucleoplasm; Golgi apparatus; extracellular space; nuclear cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nuclear speck; nucleus

Molecular Function: transferase activity; RNA polymerase subunit kinase activity; protein serine/threonine kinase activity; cyclin binding; cyclin-dependent protein kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity

Biological Process: alternative nuclear mRNA splicing, via spliceosome; RNA splicing; hemopoiesis; mRNA processing; phosphorylation; protein amino acid phosphorylation

Research Articles on Cdk13

Similar Products

Product Notes

The Cdk13 cdk13 (Catalog #AAA9208374) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 282-310. The Mouse Cdk13 Antibody (N-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Cdk13 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Cdk13 cdk13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cdk13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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