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Testing Data (Primary: Anti- CDHF14 at 1/1000 dilution)

Rabbit CDHF14 Polyclonal Antibody | anti-CDHF14 antibody

CDHF14 Polyclonal Antibody

Gene Names
FAT4; FATJ; FAT-J; CDHF14; CDHR11; HKLLS2; VMLDS2; NBLA00548
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
CDHF14; Polyclonal Antibody; CDHF14 Polyclonal Antibody; FAT4_HUMAN; Cadherin family member 14; FAT tumor suppressor homolog 4; Fat-like cadherin protein FAT-J; FATJ; hFat4; Nbla00548; Protocadherin Fat 4; anti-CDHF14 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep
Clonality
Polyclonal
Specificity
CDHF14 Polyclonal Antibody detects endogenous levels of CDHF14 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-CDHF14 antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from human CDHF14:4351-4450/4981
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Testing Data

(Primary: Anti- CDHF14 at 1/1000 dilution)

Testing Data (Primary: Anti- CDHF14 at 1/1000 dilution)
Related Product Information for anti-CDHF14 antibody
The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
542,616 Da
NCBI Official Full Name
protocadherin Fat 4 isoform 2
NCBI Official Synonym Full Names
FAT atypical cadherin 4
NCBI Official Symbol
FAT4
NCBI Official Synonym Symbols
FATJ; FAT-J; CDHF14; CDHR11; HKLLS2; VMLDS2; NBLA00548
NCBI Protein Information
protocadherin Fat 4
UniProt Protein Name
Protocadherin Fat 4
UniProt Gene Name
FAT4
UniProt Synonym Gene Names
CDHF14; FATJ; hFat4
UniProt Entry Name
FAT4_HUMAN

NCBI Description

The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014]

Uniprot Description

FAT4: May function in the regulation of planar cell polarity. Cadherins are cell-cell interaction molecules. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q28.1

Cellular Component: apical part of cell; plasma membrane; integral to membrane

Molecular Function: protein binding; calcium ion binding

Biological Process: heart morphogenesis; heterophilic cell adhesion; inner ear receptor stereocilium organization and biogenesis; plasma membrane organization and biogenesis; neurogenesis; gut development; ureteric bud branching; cerebral cortex development; homophilic cell adhesion

Disease: Van Maldergem Syndrome 2; Hennekam Lymphangiectasia-lymphedema Syndrome 2

Research Articles on CDHF14

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Product Notes

The CDHF14 fat4 (Catalog #AAA3015303) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDHF14 Polyclonal Antibody reacts with Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's CDHF14 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the CDHF14 fat4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDHF14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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