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Immunohistochemistry (IHC) (Anti-CDH12/Cadherin 12 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Rabbit anti-Human CDH12/Cadherin 12 Polyclonal Antibody | anti-CDH12 antibody

Anti-CDH12/Cadherin 12 Antibody

Gene Names
CDH12; CDHB
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Caprylic acid and ammonium sulfate precipitation
Synonyms
CDH12/Cadherin 12; Polyclonal Antibody; Anti-CDH12/Cadherin 12 Antibody; Rabbit Polyclonal to Human CDH12/Cadherin 12; CDH12; Brain cadherin; Cadherin-12; Br-cadherin; Brain-cadherin; Cadherin; neural type; 2; CDHB; N-cadherin 2; Neural type cadherin 2; Neuronal cadherin 2; anti-CDH12 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human CDH12/Cadherin 12
Purity/Purification
Caprylic acid and ammonium sulfate precipitation
Form/Format
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Sequence Length
794
Applicable Applications for anti-CDH12 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 20 ug/ml
Immunogen
Recombinant human Cadherin-12 protein.
Conjugation
Unconjugated
Preparation and Storage
Aliquot and store at -20 degree C or -80 degree C. Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-CDH12/Cadherin 12 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Immunohistochemistry (IHC) (Anti-CDH12/Cadherin 12 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Immunohistochemistry (WB)

(Anti-CDH12/Cadherin 12 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Immunohistochemistry (WB) (Anti-CDH12/Cadherin 12 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Western Blot (WB)

(Western blot of Cadherin-12 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1:10000 dilution. Predicted band size: 87 kDa. Observed band size: 87 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Western Blot (WB) (Western blot of Cadherin-12 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to rabbit IgG at 1:10000 dilution. Predicted band size: 87 kDa. Observed band size: 87 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
Related Product Information for anti-CDH12 antibody
CDH12/Cadherin 12 is a type II classical cadherin from the cadherinsuperfamily of integral membrane proteins that mediate calcium-dependentcell-cell adhesion. Mature cadherin proteins are composed of a largeN-terminal extracellular domain, a single membrane-spanning domain, and asmall, highly conserved C-terminal cytoplasmic domain. Type II(atypical) cadherins are defined based on their lack of a HAV celladhesion recognition sequence specific to type I cadherins.
Product Categories/Family for anti-CDH12 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
84,001 Da
NCBI Official Full Name
cadherin-12 isoform 1 preproprotein
NCBI Official Synonym Full Names
cadherin 12
NCBI Official Symbol
CDH12
NCBI Official Synonym Symbols
CDHB
NCBI Protein Information
cadherin-12
UniProt Protein Name
Cadherin-12
Protein Family
UniProt Gene Name
CDH12
UniProt Synonym Gene Names
BR-cadherin; N-cadherin 2

NCBI Description

This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq, Nov 2015]

Uniprot Description

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Research Articles on CDH12

Similar Products

Product Notes

The CDH12 cdh12 (Catalog #AAA2401109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CDH12/Cadherin 12 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDH12/Cadherin 12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 20 ug/ml. Researchers should empirically determine the suitability of the CDH12 cdh12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDH12/Cadherin 12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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