Western Blot (WB)
(CDCA4 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CDCA4 antibody detected the CDCA4 protein (arrow).)
Rabbit anti-Human CDCA4 Polyclonal Antibody | anti-CDCA4 antibody
CDCA4 Antibody (C-term)
Western Blot (WB)
(CDCA4 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CDCA4 antibody detected the CDCA4 protein (arrow).)
Western Blot (WB)
(CDCA4 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CDCA4 antibody detected the CDCA4 protein (arrow).)
of transcription factors. This protein regulates E2F-dependent
transcriptional activation and cell proliferation, mainly through
the E2F/retinoblastoma protein pathway. It also functions in the
regulaton of JUN oncogene expression. This protein shows
distinctive nuclear-mitotic apparatus distribution, it is involved
in spindle organization from prometaphase, and may also play a role
as a midzone factor involved in chromosome segregation or
cytokinesis. Two alternatively spliced transcript variants encoding
the same protein have been noted for this gene. Two pseudogenes
have also been identified on chromosome 1.
Wang, L., et al. Cell Motil. Cytoskeleton 65(7):581-593(2008)
Hayashi, R., et al. J. Biol. Chem. 281(47):35633-35648(2006)
Walker, M.G. Curr Cancer Drug Targets 1(1):73-83(2001)
Abdullah, J.M., et al. Blood Cells Mol. Dis. 27(3):667-676(2001)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014]
Uniprot Description
CDCA4: May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: nucleus
Molecular Function: protein binding
Research Articles on CDCA4
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Product Notes
The CDCA4 cdca4 (Catalog #AAA9200954) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 163-190. The CDCA4 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CDCA4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CDCA4 cdca4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDCA4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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