SDS-Page
(Gel: 8%SDS-PAGE Lysate: 40 ug, Lane 1-2: 293T and Hela cell lysates, Primary antibody:CDC123 antibody at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Rabbit anti-Human, Rat CDC123 Polyclonal Antibody | anti-CDC123 antibody
CDC123 Antibody
Gene Names
CDC123; D123; C10orf7
Reactivity
Human, Rat
Applications
Western Blot
Purity
Antigen affinity purification
Synonyms
CDC123; Polyclonal Antibody; CDC123 Antibody; D123; C10orf7; anti-CDC123 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CDC123 protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.3mg/ml (varies by lot)
Sequence Length
336
Applicable Applications for anti-CDC123 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:500-2000
Immunogen
Synthetic peptide of human CDC123
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C
SDS-Page
(Gel: 8%SDS-PAGE Lysate: 40 ug, Lane 1-2: 293T and Hela cell lysates, Primary antibody:CDC123 antibody at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
SDS-Page
(Gel: 8%SDS-PAGE Lysate: 40 ug, Lane 1-2: 293T and Hela cell lysates, Primary antibody:CDC123 antibody at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Related Product Information for anti-CDC123 antibody
The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc123 (Cell division cycle protein 123), also known as D123, is a 336 amino acid cytoplasmic protein that is involved in cell cycle control. Widely expressed with high expression in thymus, spleen, ovary, testis, small intestine and leukocytes, Cdc123 functions to destabilize Chfr (checkpoint with forkhead and ring finger domain) proteins which, when accumulated, block the G to S phase transition. Cdc123 prevents the Chfr proteins from collecting in the cell, thereby allowing the cell to enter the S phase. Due to its role in cell cycle control, Cdc123 is thought to be a basal marker for luminal breast cancers.
Product Categories/Family for anti-CDC123 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,135 Da
NCBI Official Full Name
cell division cycle protein 123 homolog
NCBI Official Synonym Full Names
cell division cycle 123
NCBI Official Symbol
CDC123
NCBI Official Synonym Symbols
D123; C10orf7
NCBI Protein Information
cell division cycle protein 123 homolog
UniProt Protein Name
Cell division cycle protein 123 homolog
Protein Family
UniProt Gene Name
CDC123
UniProt Synonym Gene Names
C10orf7; D123; Protein D123
UniProt Entry Name
CD123_HUMAN
Uniprot Description
CDC123: Required for S phase entry of the cell cycle. Belongs to the CDC123 family.
Chromosomal Location of Human Ortholog: 10p13
Cellular Component: cytoplasm
Biological Process: cell cycle arrest; formation of translation initiation complex; positive regulation of cell proliferation; positive regulation of translational initiation; regulation of mitotic cell cycle; regulation of translation
Research Articles on CDC123
Similar Products
Product Notes
The CDC123 cdc123 (Catalog #AAA9417279) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CDC123 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CDC123 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:500-2000. Researchers should empirically determine the suitability of the CDC123 cdc123 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDC123, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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