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Western Blot (WB) (Western Blot analysis of K562 cells using L-Selectin Polyclonal Antibody. Secondary antibody was diluted at 1:20000)

Rabbit CD62L Polyclonal Antibody | anti-CD62L antibody

CD62L Rabbit pAb

Gene Names
SELL; TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity purified
Synonyms
CD62L; Polyclonal Antibody; CD62L Rabbit pAb; L-selectin; SELL; LNHR; LYAM1; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; TQ1; gp90-MEL; anti-CD62L antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
L-Selectin Polyclonal Antibody detects endogenous levels of L-Selectin protein.
Purity/Purification
Affinity purified
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CD62L antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:100-300
ELISA: 1:20,000
Immunogen
Synthesized peptide derived from L-Selectin. at AA range: 60-140
Conjugation
Unconjugated
Nucleotide Accession
6402
Modification
Unmodified
Cell Position
Cell membrane, Membrane
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of K562 cells using L-Selectin Polyclonal Antibody. Secondary antibody was diluted at 1:20000)

Western Blot (WB) (Western Blot analysis of K562 cells using L-Selectin Polyclonal Antibody. Secondary antibody was diluted at 1:20000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded rat-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded mouse-lung, antibody was diluted at 1:100)
Product Categories/Family for anti-CD62L antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,187 Da
NCBI Official Full Name
L-selectin
NCBI Official Synonym Full Names
selectin L
NCBI Official Symbol
SELL
NCBI Official Synonym Symbols
TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1
NCBI Protein Information
L-selectin; gp90-MEL; pln homing receptor; lymph node homing receptor; lymphocyte adhesion molecule 1; leukocyte surface antigen Leu-8; CD62 antigen-like family member L; leukocyte-endothelial cell adhesion molecule 1
UniProt Protein Name
L-selectin
UniProt Gene Name
SELL
UniProt Synonym Gene Names
LNHR; LYAM1; LAM-1; LECAM1
UniProt Entry Name
LYAM1_HUMAN

NCBI Description

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

Uniprot Description

SELL: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. Belongs to the selectin/LECAM family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23-q25

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: heparin binding; protein binding; protease binding; cell adhesion molecule binding; carbohydrate binding; glycosphingolipid binding

Biological Process: regulation of immune response; cell adhesion; blood coagulation; leukocyte migration; response to ATP

Disease: Iga Nephropathy, Susceptibility To, 1

Research Articles on CD62L

Similar Products

Product Notes

The CD62L sell (Catalog #AAA4755046) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD62L Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD62L can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), ELISA (EIA). WB: 1:500-1:2000 IHC-P: 1:100-300 ELISA: 1:20,000. Researchers should empirically determine the suitability of the CD62L sell for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD62L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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