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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse liver using CD47 Polycloanl Antibody at dilution of 1:100)

Rabbit anti-Mouse CD47 Polyclonal Antibody | anti-CD47 antibody

CD47 Polyclonal Antibody

Gene Names
Cd47; IAP; Itgp; AA407862; AI848868; AW108519; 9130415E20Rik; B430305P08Rik
Reactivity
Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
CD47; Polyclonal Antibody; CD47 Polyclonal Antibody; Antigen identified by monoclonal antibody 1D8; Antigenic surface determinant protein OA3; CD 47; IAP; Integrin Associated Protein; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh related antigen; anti-CD47 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Form/Format
PBS with 0.05% Proclin300, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-CD47 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Recombinant Mouse Leukocyte surface antigen CD47 protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse liver using CD47 Polycloanl Antibody at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse liver using CD47 Polycloanl Antibody at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Mouse lung using CD47 Polycloanl Antibody at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Mouse lung using CD47 Polycloanl Antibody at dilution of 1:100)
Related Product Information for anti-CD47 antibody
CD47, also known as integrin-associated protein (IAP), is a member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. CD47 is heavily glycosylated and widely expressed by hematopoietic and nonhematopoietic cells. CD47 interacts with several membrane integrins and also acts a receptor for thrombospondin (THBS1). It is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. CD47 also functions as a ligand for signal regulatory protein-alpha (SIRPalpha). Upon binding CD47, SIRPalpha initiates a signaling cascade that results in the inhibition of phagocytosis.
Product Categories/Family for anti-CD47 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,098 Da
NCBI Official Full Name
leukocyte surface antigen CD47
NCBI Official Synonym Full Names
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
NCBI Official Symbol
Cd47
NCBI Official Synonym Symbols
IAP; Itgp; AA407862; AI848868; AW108519; 9130415E20Rik; B430305P08Rik
NCBI Protein Information
leukocyte surface antigen CD47; Rh-related antigen; integrin-associated protein
UniProt Protein Name
Leukocyte surface antigen CD47
Protein Family
UniProt Gene Name
Cd47
UniProt Synonym Gene Names
IAP
UniProt Entry Name
CD47_MOUSE

Uniprot Description

CD47: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integral

Cellular Component: membrane; integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: protein binding

Biological Process: cell migration; response to bacterium; positive regulation of phagocytosis; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; opsonization; positive regulation of T cell activation; signal transduction; cell adhesion; positive regulation of inflammatory response

Research Articles on CD47

Similar Products

Product Notes

The CD47 cd47 (Catalog #AAA2564410) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD47 Polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD47 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the CD47 cd47 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD47, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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