Rabbit CD44V10 Polyclonal Antibody
CD44V10 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1)
Reactivity
Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat
Applications
ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Flow Cytometry, Functional Assay, Immunofluorescence, immunoassay, Radioimmunoassay
Purity
PurifiedPurified
Synonyms
CD44V10; Polyclonal Antibody; CD44V10 (HCAM; Homing Cell Adhesion Molecule; Pgp-1; Phagocytic Glycoprotein-1; Hermes Antigen; Lymphocyte Homing Receptor; ECM-III; HUTCH-1); Anti -CD44V10 (HCAM; anti-CD44V10 antibody
Host
Rabbit
Reactivity
Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human CD44v10 (~116kD). Species Crossreactivity: rabbit, porcine, mouse, rat, canine and bovine.
Purity/Purification
Purified
Purified
Purified
Form/Format
Supplied as a liquid in PBS, 0.01% sodium azide.
Applicable Applications for anti-CD44V10 antibody
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Radioimmunoassay (RIA)
Application Notes
Suitable for use in Immunofluorescence, Flow Cytometry, ELISA, Western Blot, Immunoprecipitation, RIA and Immunohistochemistry.
Dilution: Immunofluorescence: 1:200
Flow Cytometry: 1:1000
ELISA: 1:2000
Western Blot: 1:10,000
Immunohistochemistry (Paraffin): 1:250
Immunoprecipitation: 1:200
RIA: 1:5000
Dilution: Immunofluorescence: 1:200
Flow Cytometry: 1:1000
ELISA: 1:2000
Western Blot: 1:10,000
Immunohistochemistry (Paraffin): 1:250
Immunoprecipitation: 1:200
RIA: 1:5000
Immunogen
Synthetic peptide corresponding to human CD44v10.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-CD44V10 antibody
Recent studies indicate that the expression of CD44 on the cell surface changes profoundly during tumor metastasis, particularly during the progression of various carcinomas. Sequencing analysis reveals that CD44 exists in different forms (at least 15 isoforms have been identified) that are variants of the common or standard hemopoietic form CD44s. Specifically, the human CD44 gene contains 19 exons, out of which 10 exons can potentially be alternatively spliced. In particular, CD44s contains exons 1-15 and exons 15-19. The other exons (e.g. 6-14) are also spliced in a variety of different cells. For example, epithelial cells contain exons 12-14 inserted into the CD44s transcripts. This isoform has been designated as CD44E. Other CD44 variants CD44v) have the same sequences at the two ends of the molecule, but differ in a middle region (with different numbers of additional exons) located on the external side of the cell membrane. It has been suggested that expression of CD44 variants with the additional exon 14 (so-called v10) is responsible for tumor progression and metastasis. In fact, CD44v10 expression has been used as an indicator of metastasis.
Product Categories/Family for anti-CD44V10 antibody
Similar Products
Product Notes
The CD44V10 (Catalog #AAA614594) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD44V10 (HCAM, Homing Cell Adhesion Molecule, Pgp-1, Phagocytic Glycoprotein-1, Hermes Antigen, Lymphocyte Homing Receptor, ECM-III, HUTCH-1) reacts with Bovine, Canine, Human, Mouse, Porcine, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD44V10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Radioimmunoassay (RIA). Suitable for use in Immunofluorescence, Flow Cytometry, ELISA, Western Blot, Immunoprecipitation, RIA and Immunohistochemistry. Dilution: Immunofluorescence: 1:200 Flow Cytometry: 1:1000 ELISA: 1:2000 Western Blot: 1:10,000 Immunohistochemistry (Paraffin): 1:250 Immunoprecipitation: 1:200 RIA: 1:5000. Researchers should empirically determine the suitability of the CD44V10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD44V10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
