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Western Blot (WB) (Western blot analysis CD300A using K562 whole cell lysates)

Rabbit anti-Human CD300A Polyclonal Antibody | anti-CD300A antibody

CD300A Antibody

Gene Names
CD300A; IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9
Reactivity
Human
Applications
Western Blot
Synonyms
CD300A; Polyclonal Antibody; CD300A Antibody; CD300a antigen; CD300a molecule; CMRF35-like molecule 8; CMRF35-H; CMRF35-H9; CLM-8; CMRF35H9; IGSF12; Inhibitory receptor protein 60; IRC2; IRC1; NK inhibitory receptor; CMRF-35-H9; CMRF-35H; CMRF35H; IRC1a; IRp60; Leukocyte membrane antigen; anti-CD300A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
CD300A Antibody detects endogenous levels of total CD300A
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
186
Applicable Applications for anti-CD300A antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human CD300A
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis CD300A using K562 whole cell lysates)

Western Blot (WB) (Western blot analysis CD300A using K562 whole cell lysates)
Product Categories/Family for anti-CD300A antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,517 Da
NCBI Official Full Name
CMRF35-like molecule 8 isoform 2
NCBI Official Synonym Full Names
CD300a molecule
NCBI Official Symbol
CD300A
NCBI Official Synonym Symbols
IRC1; IRC2; CLM-8; IRp60; IGSF12; CMRF35H; CMRF-35H; CMRF35-H; CMRF35H9; CMRF35-H9; IRC1/IRC2; CMRF-35-H9
NCBI Protein Information
CMRF35-like molecule 8
UniProt Protein Name
CMRF35-like molecule 8
Protein Family
UniProt Gene Name
CD300A
UniProt Synonym Gene Names
CMRF35H; IGSF12; CLM-8; CMRF35-H9; IgSF12; IRp60
UniProt Entry Name
CLM8_HUMAN

NCBI Description

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Uniprot Description

MAIR-I: Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Belongs to the CD300 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: membrane; plasma membrane

Molecular Function: phosphatidylethanolamine binding; phosphatidylserine binding; protein binding

Biological Process: negative regulation of B cell proliferation; negative regulation of B cell receptor signaling pathway; negative regulation of fibroblast proliferation; negative regulation of MAP kinase activity; negative regulation of mast cell activation during immune response; negative regulation of mast cell degranulation; negative regulation of NK T cell activation; negative regulation of phagocytosis, engulfment; positive regulation of phosphoprotein phosphatase activity; regulation of immune response; regulation of T cell receptor signaling pathway

Research Articles on CD300A

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Product Notes

The CD300A cd300a (Catalog #AAA9418696) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD300A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD300A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the CD300A cd300a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD300A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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