Western Blot (WB)
(Western blot analysis CD2L7 using HUVEC whole cell lysates)
Rabbit anti-Human, Rat CD2L7 Polyclonal Antibody | anti-CD2L7 antibody
CD2L7 Antibody
Gene Names
CDK12; CRK7; CRKR; CRKRS
Reactivity
Human, Rat
Applications
Western Blot
Synonyms
CD2L7; Polyclonal Antibody; CD2L7 Antibody; CDK12; CDC2-related protein kinase 7; CRK7; Cyclin-dependent kinase 12; HCDK12; KIAA0904; CRKR; CRKRS; Pksc; anti-CD2L7 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Specificity
CD2L7 Antibody detects endogenous levels of total CD2L7
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
1481
Applicable Applications for anti-CD2L7 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human CD2L7
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C
Western Blot (WB)
(Western blot analysis CD2L7 using HUVEC whole cell lysates)
Western Blot (WB)
(Western blot analysis CD2L7 using HUVEC whole cell lysates)
Product Categories/Family for anti-CD2L7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
141,449 Da
NCBI Official Full Name
cyclin-dependent kinase 12 isoform 2
NCBI Official Synonym Full Names
cyclin dependent kinase 12
NCBI Official Symbol
CDK12
NCBI Official Synonym Symbols
CRK7; CRKR; CRKRS
NCBI Protein Information
cyclin-dependent kinase 12
UniProt Protein Name
Cyclin-dependent kinase 12
UniProt Gene Name
CDK12
UniProt Synonym Gene Names
CRK7; CRKRS; KIAA0904; CrkRS; CDC2-related protein kinase 7; hCDK12
UniProt Entry Name
CDK12_HUMAN
Uniprot Description
Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Research Articles on CD2L7
Similar Products
Product Notes
The CD2L7 cdk12 (Catalog #AAA9417854) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD2L7 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD2L7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the CD2L7 cdk12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD2L7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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