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Rabbit CD1C Polyclonal Antibody | anti-CD1C antibody

CD1C

Gene Names
CD1C; R7; CD1; CD1A; BDCA1
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Protein A/G Column
Synonyms
CD1C; Polyclonal Antibody; anti-CD1C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Protein A/G Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
1054
Applicable Applications for anti-CD1C antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20000-80000
WB: 1:200-1,000
Immunogen
Recombinant fragment corresponding to 67-247aa of human CD1C.
Cellular Localization
Cell Membrane, Endosome Membrane, Lysosome
Related Product Information for anti-CD1C antibody
Homo sapiens CD1c molecule, mRNA
References
Lepore M, de Lalla C, Gundimeda SR, Gsellinger H, Consonni M, Garavaglia C, Sansano S, Piccolo F, Scelfo A, Hussinger D, et al. A novel self-lipid antigen targets human T cells against CD1c(+) leukemias. 211(7):1363-1377 (2015)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
911
Molecular Weight
38KD
NCBI Official Full Name
Homo sapiens CD1c molecule, mRNA
NCBI Official Synonym Full Names
CD1c molecule
NCBI Official Symbol
CD1C
NCBI Official Synonym Symbols
R7; CD1; CD1A; BDCA1
NCBI Protein Information
T-cell surface glycoprotein CD1c

NCBI Description

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Research Articles on CD1C

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Product Notes

The CD1C (Catalog #AAA8562300) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD1C reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD1C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20000-80000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the CD1C for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD1C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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