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Western Blot (WB) (Western blot analysis of CD160 in K562 cell lysate with CD160 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Rabbit anti-Human, Mouse CD160 Polyclonal Antibody | anti-CD160 antibody

CD160 Antibody

Gene Names
CD160; NK1; BY55; NK28
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunofluorescence
Purity
CD160 Antibody is affinity chromatography purified via peptide column.
Synonyms
CD160; Polyclonal Antibody; CD160 Antibody; CD160 Antibody : NK1; BY55; NK28; CD160 antigen; Natural killer cell receptor BY55; CD160 molecule; anti-CD160 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
CD160 antibody is human and mouse reactive. Multiple isoforms of CD160 are known to exist.
Purity/Purification
CD160 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
181
Applicable Applications for anti-CD160 antibody
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
CD160 antibody can be used for detection of CD160 by Western blot at 1 - 2 mug/ml.
Conjugate
Unconjugated
Immunogen
CD160 antibody was raised against a 17 amino acid peptide near the center of human CD160.
Buffer
CD160 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
CD160 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

Western Blot (WB)

(Western blot analysis of CD160 in K562 cell lysate with CD160 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot analysis of CD160 in K562 cell lysate with CD160 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Immunofluorescence (IF)

(Immunofluorescence of CD160 in Jurkat cells tissue with CD160 antibody at 5 μg/mL.)

Immunofluorescence (IF) (Immunofluorescence of CD160 in Jurkat cells tissue with CD160 antibody at 5 μg/mL.)
Related Product Information for anti-CD160 antibody
CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1). It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2). CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2,3). Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 20 kDa

Observed: 25kDa
NCBI Official Full Name
CD160 antigen
NCBI Official Synonym Full Names
CD160 molecule
NCBI Official Symbol
CD160
NCBI Official Synonym Symbols
NK1; BY55; NK28
NCBI Protein Information
CD160 antigen; CD160-delta Ig; CD160 transmembrane isoform; natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member
UniProt Protein Name
CD160 antigen
Protein Family
UniProt Gene Name
CD160
UniProt Synonym Gene Names
BY55
UniProt Entry Name
BY55_HUMAN

NCBI Description

CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]

Uniprot Description

Receptor showing broad specificity for both classical and non-classical MHC class I molecules.

Research Articles on CD160

Similar Products

Product Notes

The CD160 cd160 (Catalog #AAA153548) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD160 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD160 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). CD160 antibody can be used for detection of CD160 by Western blot at 1 - 2 mug/ml. Researchers should empirically determine the suitability of the CD160 cd160 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD160, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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