Western Blot (WB)
(Western blot analysis of CD109 expression in Mouse cerebellum tissue lysate, The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human, Mouse CD109 Polyclonal Antibody | anti-CD109 antibody
CD109 Antibody
Gene Names
CD109; p180; r150; CPAMD7
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
CD109; Polyclonal Antibody; CD109 Antibody; 150 KDa TGF beta 1 binding protein; 150 KDa TGF-beta-1-binding protein; 7D1; 8A3; Activated T cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD 109; CD109 antigen; CD109_HUMAN; CPAMD7; DKFZp762L1111; E123; FLJ38569; FLJ41966; Gov system alloantigens on platelets; p180; Platelet specific Gov antigen; Platelet-specific Gov antigen; r150; RP11 525G3.1; anti-CD109 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
CD109 antibody detects endogenous levels of total CD109
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1428
Applicable Applications for anti-CD109 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Cell Membrane
Tissue Specificity
Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34+ acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and activated platelets. Isoform 4 is expressed in placenta. Isoform 1 is expressed in keratinocytes and placenta.
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of CD109 expression in Mouse cerebellum tissue lysate, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of CD109 expression in Mouse cerebellum tissue lysate, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-CD109 antibody
Function: Modulates negatively TGFB1 signaling in keratinocytes.
Subunit Structure: Heterodimer; disulfide-linked. Interacts with TGFB1 and TGFBR1. Forms a heteromeric complex with TGFBR1, TGFBR2 and TGFBR3 in a ligand-independent manner.
Post-translational Modifications: N-glycosylated. 2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form.
Similarity: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
Subunit Structure: Heterodimer; disulfide-linked. Interacts with TGFB1 and TGFBR1. Forms a heteromeric complex with TGFBR1, TGFBR2 and TGFBR3 in a ligand-independent manner.
Post-translational Modifications: N-glycosylated. 2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form.
Similarity: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 162 kDa
Predicted: 162 kDa
Predicted: 162 kDa
NCBI Official Full Name
CD109 antigen isoform 2 preproprotein
NCBI Official Synonym Full Names
CD109 molecule
NCBI Official Symbol
CD109
NCBI Official Synonym Symbols
p180; r150; CPAMD7
NCBI Protein Information
CD109 antigen
UniProt Protein Name
CD109 antigen
Protein Family
UniProt Gene Name
CD109
UniProt Synonym Gene Names
CPAMD7
NCBI Description
This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Uniprot Description
Modulates negatively TGFB1 signaling in keratinocytes.
Research Articles on CD109
Similar Products
Product Notes
The CD109 cd109 (Catalog #AAA9603824) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD109 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD109 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CD109 cd109 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD109, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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