Rabbit CCT7 Polyclonal Antibody | anti-CCT7 antibody

CCT7 Antibody

Cat. Num. AAA7117869

• Gene Names: CCT7; CCTH; CCTETA; NIP7-1; TCP1ETA
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: CCT7; Polyclonal Antibody; CCT7 Antibody; CCTH; NIP7-1; T-complex protein 1 subunit eta; TCP-1-eta; CCT-eta; HIV-1 Nef-interacting protein; anti-CCT7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

• Applicable Applications for anti-CCT7 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; ELISA: 1:5000
• Immunogen: Synthesized peptide derived from the Internal region of human TCP-1 eta.
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of HeLa cells using TCP-1 Polyclonal Antibody)

Product Categories/Family for anti-CCT7 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 58331185
• NCBI GeneID: 10574
• NCBI Accession #: NP_001009570.1
• NCBI GenBank Nucleotide #: NM_001009570.2
• UniProt Accession #: Q99832; O14871; Q6FI26; A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7
• Molecular Weight: 59,367 Da
• NCBI Official Full Name: T-complex protein 1 subunit eta isoform b
• NCBI Official Synonym Full Names: chaperonin containing TCP1, subunit 7 (eta)
• NCBI Official Symbol: CCT7
• NCBI Official Synonym Symbols: CCTH; CCTETA; NIP7-1; TCP1ETA
• NCBI Protein Information: T-complex protein 1 subunit eta; CCT-eta; TCP-1-eta; HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; chaperonin containing t-complex polypeptide 1, eta subunit
• UniProt Protein Name: T-complex protein 1 subunit eta
• Protein Family: Probable T-complex protein
• UniProt Gene Name: CCT7
• UniProt Synonym Gene Names: CCTH; NIP7-1; TCP-1-eta
• UniProt Entry Name: TCPH_HUMAN

NCBI Description

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq, Oct 2009]

Uniprot Description

CCT-eta: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Belongs to the TCP-1 chaperonin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 2p13.2

Cellular Component: chaperonin-containing T-complex; microtubule; mitochondrion; cytoplasm; cytosol

Molecular Function: identical protein binding; protein binding; unfolded protein binding; ATP binding

Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; binding of sperm to zona pellucida