Rabbit anti-Human CCT6B Polyclonal Antibody | anti-CCT6B antibody

CCT6B Antibody

Cat. Num. AAA1495758

• Gene Names: CCT6B; Cctz2; CCTZ-2; TSA303; CCT-zeta-2; TCP-1-zeta-2
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: >95%, Protein G Purified
• Synonyms: CCT6B; Polyclonal Antibody; CCT6B Antibody; T-complex protein 1 subunit zeta-2; TCP-1-zeta-2; CCT-zeta-2; CCT-zeta-like; TCP-1-zeta-like; Testis-specific Tcp20; Testis-specific protein TSA303; anti-CCT6B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G Purified
• Sequence Length: 493

• Applicable Applications for anti-CCT6B antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: IHC:1:20-1:200
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Conjugate: Non-conjugated
• Immunogen: Recombinant human T-complex protein 1 subunit zeta-2 protein
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS1495758 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS1495758 at dilution of 1:100)

Related Product Information for anti-CCT6B antibody

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 302058290
• NCBI GeneID: 10693
• NCBI Accession #: NP_001180458.1
• NCBI GenBank Nucleotide #: NM_001193529.2
• UniProt Accession #: Q92526; Q8TC34; B4DX20; B4DYB0
• Molecular Weight: 53,586 Da
• NCBI Official Full Name: T-complex protein 1 subunit zeta-2 isoform 2
• NCBI Official Synonym Full Names: chaperonin containing TCP1 subunit 6B
• NCBI Official Symbol: CCT6B
• NCBI Official Synonym Symbols: Cctz2; CCTZ-2; TSA303; CCT-zeta-2; TCP-1-zeta-2
• NCBI Protein Information: T-complex protein 1 subunit zeta-2
• UniProt Protein Name: T-complex protein 1 subunit zeta-2
• Protein Family: T-complex protein
• UniProt Gene Name: CCT6B
• UniProt Synonym Gene Names: TCP-1-zeta-2
• UniProt Entry Name: TCPW_HUMAN

NCBI Description

This gene encodes a molecular chaperone that is a member of the chaperonin-containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Uniprot Description

CCT-zeta-2: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Belongs to the TCP-1 chaperonin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: chaperonin-containing T-complex; cytoplasm

Molecular Function: ATP binding; protein transporter activity; unfolded protein binding

Biological Process: chaperone-mediated protein complex assembly; protein folding; protein transport; spermatogenesis