Rabbit CCRN4L Polyclonal Antibody | anti-CCRN4L antibody
CCRN4L Antibody
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008]
Uniprot Description
CCRN4L: Component of the circadian clock or downstream effector of clock function. Exhibits a high amplitude circadian rhythm with maximal levels in early evening. In constant darkness or constant light, the amplitude of the rhythm decreases. Belongs to the CCR4/nocturin family.
Protein type: EC 3.1.13.4
Chromosomal Location of Human Ortholog: 4q31.1
Cellular Component: cytoplasm; nucleoplasm; nucleus; perinuclear region of cytoplasm
Molecular Function: mRNA binding; poly(A)-specific ribonuclease activity; transcription factor activity
Biological Process: circadian regulation of gene expression; circadian rhythm; mRNA stabilization; negative regulation of osteoblast differentiation; positive regulation of fat cell differentiation; regulation of circadian rhythm; response to extracellular stimulus; response to lipopolysaccharide; transcription from RNA polymerase II promoter
Research Articles on CCRN4L
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Product Notes
The CCRN4L noct (Catalog #AAA9418917) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCRN4L Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CCRN4L can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the CCRN4L noct for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCRN4L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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