Western Blot (WB)
(Western blot analysis of CCRK expression in RPMI-8226 cell lysate ; ;, The lane on the left is treated with the antigen-specific peptide.)
Rabbit CCRK Polyclonal Antibody | anti-CCRK antibody
CCRK Antibody
Gene Names
CDK20; P42; CCRK; CDCH; PNQALRE
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
CCRK; Polyclonal Antibody; CCRK Antibody; CAK kinase p42; CAK-kinase p42; CDCH; CDK activating kinase p42; CDK-activating kinase p42; cdk20; CDK20_HUMAN; Cell cycle related kinase; Cell cycle-related kinase; Cell division protein kinase 20; Cyclin dependent protein kinase H; Cyclin kinase activating kinase p42; Cyclin-dependent kinase 20; Cyclin-dependent protein kinase H; Cyclin-kinase-activating kinase p42; p42; PNQALRE; anti-CCRK antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
CCRK antibody detects endogenous levels of total CCRK
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
346
Applicable Applications for anti-CCRK antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Nucleus. Cytoplasm. Cell Projection > Cilium.
Predicted Cross Reactivity
Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Xenopus
Similarity
Pig (92%), Zebrafish (92%), Bovine (92%), Sheep (92%), Rabbit (100%), Dog (100%), Xenopus (92%)
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of CCRK expression in RPMI-8226 cell lysate ; ;, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of CCRK expression in RPMI-8226 cell lysate ; ;, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-CCRK antibody
Function: Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
Subunit Structure: Monomer. Interacts with TBC1D32 (By similarity). Interacts with MAK.
Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Subunit Structure: Monomer. Interacts with TBC1D32 (By similarity). Interacts with MAK.
Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 39 kDa
Predicted: 39 kDa
Predicted: 39 kDa
NCBI Official Full Name
cyclin-dependent kinase 20 isoform 3
NCBI Official Synonym Full Names
cyclin dependent kinase 20
NCBI Official Symbol
CDK20
NCBI Official Synonym Symbols
P42; CCRK; CDCH; PNQALRE
NCBI Protein Information
cyclin-dependent kinase 20
UniProt Protein Name
Cyclin-dependent kinase 20
UniProt Gene Name
CDK20
UniProt Synonym Gene Names
CCRK; CDCH; CAK-kinase p42
NCBI Description
The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Dec 2009]
Uniprot Description
Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
Research Articles on CCRK
Similar Products
Product Notes
The CCRK cdk20 (Catalog #AAA9604174) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCRK Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CCRK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CCRK cdk20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCRK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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