Testing Data
Rabbit CCR4 Polyclonal Antibody | anti-CCR4 antibody
CCR4 Antibody
Reactivity
Human, Mouse, Dog
Applications
Western Blot
Purity
Affinity purified
Synonyms
CCR4; Polyclonal Antibody; CCR4 Antibody; C-C chemokine receptor 4; CCR 4; chemokine C C motif receptor 4; C-C CKR-4; K5-5; anti-CCR4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Dog
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
837
Applicable Applications for anti-CCR4 antibody
Western Blot (WB)
Application Notes
Western blotting (2-6 ug/ml). However, the optimal concentrations should be determined individually.
Immunogen
Synthetic peptide surrounding amino acid 32 of human CCR4
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for anti-CCR4 antibody
Background: CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
94,670 Da
NCBI Official Full Name
CCR4
UniProt Protein Name
Glucose-repressible alcohol dehydrogenase transcriptional effector
Protein Family
UniProt Gene Name
CCR4
UniProt Entry Name
CCR4_YEAST
Uniprot Description
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. CCR4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth and it mediates or is required for the action of the SPT6 and SPT10 genes.
Similar Products
Product Notes
The CCR4 ccr4 (Catalog #AAA840622) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCR4 Antibody reacts with Human, Mouse, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's CCR4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (2-6 ug/ml). However, the optimal concentrations should be determined individually. Researchers should empirically determine the suitability of the CCR4 ccr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCR4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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