Western Blot (WB)
(Western Blot analysis of CCL23 expression in transfected 293T cell line by CCL23 polyclonal antibody. Lane 1: CCL23 transfected lysate (15.3kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human CCL23 Polyclonal Antibody | anti-CCL23 antibody
CCL23 (C-C Motif Chemokine 23, CK-beta-8, CKB-8, Macrophage Inflammatory Protein 3, MIP-3, Myeloid Progenitor Inhibitory Factor 1, MPIF-1, Small-inducible Cytokine A23, MIP3, MPIF1, SCYA23)
Serum
Serum
Western Blot (WB)
(Western Blot analysis of CCL23 expression in transfected 293T cell line by CCL23 polyclonal antibody. Lane 1: CCL23 transfected lysate (15.3kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of CCL23 expression in transfected 293T cell line by CCL23 polyclonal antibody. Lane 1: CCL23 transfected lysate (15.3kD). Lane 2: Non-transfected lysate.)
Immunoprecipitation (IP)
(Immunoprecipitation of CCL23 transfected lysate using CCL23 rabbit polyclonal antibody and Protein A Magnetic Bead and immunoblotted with CCL23 mouse polyclonal antibody.)
Immunoprecipitation (IP)
(Immunoprecipitation of CCL23 transfected lysate using CCL23 rabbit polyclonal antibody and Protein A Magnetic Bead and immunoblotted with CCL23 mouse polyclonal antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
Uniprot Description
CCL6: Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q12
Cellular Component: extracellular space; extracellular region
Molecular Function: heparin binding; CCR1 chemokine receptor binding; chemokine activity
Biological Process: cellular calcium ion homeostasis; G-protein coupled receptor protein signaling pathway; monocyte chemotaxis; negative regulation of cell proliferation; cell-cell signaling; immune response; inflammatory response; signal transduction; chemotaxis
Research Articles on CCL23
Similar Products
Product Notes
The CCL23 ccl23 (Catalog #AAA6000556) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCL23 (C-C Motif Chemokine 23, CK-beta-8, CKB-8, Macrophage Inflammatory Protein 3, MIP-3, Myeloid Progenitor Inhibitory Factor 1, MPIF-1, Small-inducible Cytokine A23, MIP3, MPIF1, SCYA23) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCL23 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). Suitable for use in Western Blot and Immunoprecipitation. Researchers should empirically determine the suitability of the CCL23 ccl23 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MKVSVAALSC LMLVTALGSQ ARVTKDAETE FMMSKLPLEN PVLLDMLWRR KIGPQMTLSH AAGFHATSAD CCISYTPRSI PCSLLESYFE TNSECSKPGV IFLTKKGRRF CANPSDKQVQ VCVRMLKLDT RIKTRKN. It is sometimes possible for the material contained within the vial of "CCL23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
