Rabbit anti-Human CCL15 Polyclonal Antibody | anti-CCL15 antibody

CCL15 Antibody

Cat. Num. AAA7122909

• Gene Names: CCL15; LKN1; NCC3; SY15; HCC-2; LKN-1; MIP-5; NCC-3; SCYL3; MIP-1D; MRP-2B; SCYA15; HMRP-2B; MIP-1 delta
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• Synonyms: CCL15; Polyclonal Antibody; CCL15 Antibody; C-C motif chemokine 15 (Chemokine CC-2) (HCC-2) (Leukotactin-1) (LKN-1) (MIP-1 delta) (Macrophage inflammatory protein 5) (MIP-5) (Mrp-2b) (NCC-3) (Small-inducible cytokine A15) [Cleaved into: CCL15(22-92); CCL15(25-92); CCL15(29-92)]; anti-CCL15 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, Containing 0.02% Sodium Azide as Preservative and 50% Glycerol.

• Applicable Applications for anti-CCL15 antibody: Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
• Application Notes: IHC-P: 1:50-300; ELISA: 1:10000-20000
• Immunogen: Synthetic peptide from human protein at AA range: 51-100
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200)

Product Categories/Family for anti-CCL15 antibody

Immunology

NCBI and Uniprot Product Information

• NCBI GI #: 597709818
• NCBI GeneID: 6359
• NCBI Accession #: NP_116741.2
• NCBI GenBank Nucleotide #: NM_032965.5
• UniProt Accession #: Q16663; Q9UM74; B2RU34; E1P651
• Molecular Weight: 12,248 Da
• NCBI Official Full Name: C-C motif chemokine 15 preproprotein
• NCBI Official Synonym Full Names: chemokine (C-C motif) ligand 15
• NCBI Official Symbol: CCL15
• NCBI Official Synonym Symbols: LKN1; NCC3; SY15; HCC-2; LKN-1; MIP-5; NCC-3; SCYL3; MIP-1D; MRP-2B; SCYA15; HMRP-2B; MIP-1 delta
• NCBI Protein Information: C-C motif chemokine 15; chemokine CC-2; leukotactin 1; macrophage inflammatory protein 5; new CC chemokine 3; small inducible cytokine subfamily A (Cys-Cys), member 15; small-inducible cytokine A15
• UniProt Protein Name: C-C motif chemokine 15
• Protein Family: C-C motif chemokine
• UniProt Gene Name: CCL15
• UniProt Synonym Gene Names: MIP5; NCC3; SCYA15; HCC-2; LKN-1; MIP-5
• UniProt Entry Name: CCL15_HUMAN

NCBI Description

This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14). [provided by RefSeq, Jan 2013]

Uniprot Description

CCL15: Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: extracellular space

Molecular Function: heparin binding; chemokine activity; receptor binding; chemoattractant activity

Biological Process: cellular calcium ion homeostasis; cell-cell signaling; positive chemotaxis; immune response; signal transduction; chemotaxis